NRL (gene)

NRL (gene)
Neural retina leucine zipper
Symbols NRL; D14S46E; NRL-MAF; RP27
External IDs OMIM162080 MGI102567 HomoloGene4501 GeneCards: NRL Gene
RNA expression pattern
PBB GE NRL 206596 s at tn.png
PBB GE NRL 206597 at tn.png
More reference expression data
Species Human Mouse
Entrez 4901 18185
Ensembl ENSG00000129535 ENSMUSG00000040632
UniProt P54845 Q543Y0
RefSeq (mRNA) NM_006177 XM_977385
RefSeq (protein) NP_006168 XP_982479
Location (UCSC) Chr 14:
24.55 – 24.58 Mb
Chr 14:
56.14 – 56.14 Mb
PubMed search [1] [2]

Neural retina-specific leucine zipper protein is a protein that in humans is encoded by the NRL gene.[1][2][3]

This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases.[3]


See also


  1. ^ Yang-Feng TL, Swaroop A (Dec 1992). "Neural retina-specific leucine zipper gene NRL (D14S46E) maps to human chromosome 14q11.1-q11.2". Genomics 14 (2): 491–2. doi:10.1016/S0888-7543(05)80248-4. PMID 1427865. 
  2. ^ Bessant DA, Payne AM, Mitton KP, Wang QL, Swain PK, Plant C, Bird AC, Zack DJ, Swaroop A, Bhattacharya SS (Apr 1999). "A mutation in NRL is associated with autosomal dominant retinitis pigmentosa". Nat Genet 21 (4): 355–6. doi:10.1038/7678. PMID 10192380. 
  3. ^ a b "Entrez Gene: NRL neural retina leucine zipper". 

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • NRL (disambiguation) — NRL may refer to: Contents 1 Sports leagues 2 Other uses 3 See also …   Wikipedia

  • Gene Miles — Infobox rugby league biography playername = Gene Miles fullname = Gene Miles nickname = Geno, Big Unit caption = dateofbirth = 21 July, 1959 placeofbirth = Townsville countryofbirth = Australia height = weight = position = rlp|CE|SR retired = yes …   Wikipedia

  • Gene Miles — Pour les articles homonymes, voir Miles. Infobox Rugbyman Gene Miles …   Wikipédia en Français

  • MAF (gene) — V maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) Identifiers Symbols MAF; MGC71685; c MAF External IDs …   Wikipedia

  • CRX (gene) — Cone rod homeobox, also known as CRX, is a human gene.cite web | title = Entrez Gene: CRX cone rod homeobox| url = Cmd=ShowDetailView TermToSearch=1406| accessdate = ] PBB Summary section title =… …   Wikipedia

  • DLX3 (gene) — Distal less homeobox 3 Identifiers Symbols DLX3; AI4; TDO External IDs OMIM: …   Wikipedia

  • MLL (gene) — HRX redirects here. For the bank holding, see Hypo Real Estate. Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila) PDB rendering based on 2j2s …   Wikipedia

  • DBP (gene) — D site of albumin promoter (albumin D box) binding protein Identifiers Symbols DBP; DABP External IDs …   Wikipedia

  • V-erbA-related gene — Nuclear receptor subfamily 2, group F, member 6 Identifiers Symbols NR2F6; EAR 2; EAR2; ERBAL2 External IDs …   Wikipedia

  • NFIB (gene) — Nuclear factor I/B Identifiers Symbols NFIB; HMGIC/NFIB; NFI RED; NFIB2; NFIB3 External IDs …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”