- YY1
YY1 transcription factor, also known as YY1, is a human
gene .PBB_Summary
section_title =
summary_text = YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [cite web | title = Entrez Gene: YY1 YY1 transcription factor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7528| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Thomas MJ, Seto E |title=Unlocking the mechanisms of transcription factor YY1: are chromatin modifying enzymes the key? |journal=Gene |volume=236 |issue= 2 |pages= 197–208 |year= 1999 |pmid= 10452940 |doi=
*cite journal | author=Shi Y, Seto E, Chang LS, Shenk T |title=Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein. |journal=Cell |volume=67 |issue= 2 |pages= 377–88 |year= 1991 |pmid= 1655281 |doi=
*cite journal | author=Park K, Atchison ML |title=Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 21 |pages= 9804–8 |year= 1991 |pmid= 1946405 |doi=
*cite journal | author=Yang WM, Inouye CJ, Seto E |title=Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activity. |journal=J. Biol. Chem. |volume=270 |issue= 25 |pages= 15187–93 |year= 1995 |pmid= 7541038 |doi=
*cite journal | author=Lee JS, Galvin KM, See RH, "et al." |title=Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300. |journal=Genes Dev. |volume=9 |issue= 10 |pages= 1188–98 |year= 1995 |pmid= 7758944 |doi=
*cite journal | author=Zhou Q, Gedrich RW, Engel DA |title=Transcriptional repression of the c-fos gene by YY1 is mediated by a direct interaction with ATF/CREB. |journal=J. Virol. |volume=69 |issue= 7 |pages= 4323–30 |year= 1995 |pmid= 7769693 |doi=
*cite journal | author=Zhu W, Lossie AC, Camper SA, Gumucio DL |title=Chromosomal localization of the transcription factor YY1 in the mouse and human. |journal=Mamm. Genome |volume=5 |issue= 4 |pages= 234–6 |year= 1994 |pmid= 7912122 |doi=
*cite journal | author=Shrivastava A, Saleque S, Kalpana GV, "et al." |title=Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc. |journal=Science |volume=262 |issue= 5141 |pages= 1889–92 |year= 1994 |pmid= 8266081 |doi=
*cite journal | author=Becker KG, Swergold GD, Ozato K, Thayer RE |title=Binding of the ubiquitous nuclear transcription factor YY1 to a cis regulatory sequence in the human LINE-1 transposable element. |journal=Hum. Mol. Genet. |volume=2 |issue= 10 |pages= 1697–702 |year= 1994 |pmid= 8268924 |doi=
*cite journal | author=Margolis DM, Somasundaran M, Green MR |title=Human transcription factor YY1 represses human immunodeficiency virus type 1 transcription and virion production. |journal=J. Virol. |volume=68 |issue= 2 |pages= 905–10 |year= 1994 |pmid= 8289393 |doi=
*cite journal | author=Lee JS, Galvin KM, Shi Y |title=Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 13 |pages= 6145–9 |year= 1993 |pmid= 8327494 |doi=
*cite journal | author=Yang WM, Inouye C, Zeng Y, "et al." |title=Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 23 |pages= 12845–50 |year= 1996 |pmid= 8917507 |doi=
*cite journal | author=Houbaviy HB, Usheva A, Shenk T, Burley SK |title=Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 24 |pages= 13577–82 |year= 1997 |pmid= 8942976 |doi=
*cite journal | author=Kalenik JL, Chen D, Bradley ME, "et al." |title=Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional transcription factor YY1. |journal=Nucleic Acids Res. |volume=25 |issue= 4 |pages= 843–9 |year= 1997 |pmid= 9016636 |doi=
*cite journal | author=Cole EG, Gaston K |title=A functional YY1 binding site is necessary and sufficient to activate Surf-1 promoter activity in response to serum growth factors. |journal=Nucleic Acids Res. |volume=25 |issue= 18 |pages= 3705–11 |year= 1997 |pmid= 9278494 |doi=
*cite journal | author=Yang WM, Yao YL, Sun JM, "et al." |title=Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family. |journal=J. Biol. Chem. |volume=272 |issue= 44 |pages= 28001–7 |year= 1997 |pmid= 9346952 |doi=
*cite journal | author=Romerio F, Gabriel MN, Margolis DM |title=Repression of human immunodeficiency virus type 1 through the novel cooperation of human factors YY1 and LSF. |journal=J. Virol. |volume=71 |issue= 12 |pages= 9375–82 |year= 1997 |pmid= 9371597 |doi=
*cite journal | author=McNeil S, Guo B, Stein JL, "et al." |title=Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: the C-terminus is a principal determinant for nuclear trafficking. |journal=J. Cell. Biochem. |volume=68 |issue= 4 |pages= 500–10 |year= 1998 |pmid= 9493912 |doi=
*cite journal | author=Viles JH, Patel SU, Mitchell JB, "et al." |title=Design, synthesis and structure of a zinc finger with an artificial beta-turn. |journal=J. Mol. Biol. |volume=279 |issue= 4 |pages= 973–86 |year= 1998 |pmid= 9642075 |doi= 10.1006/jmbi.1998.1764
*cite journal | author=Yao YL, Dupont BR, Ghosh S, "et al." |title=Cloning, chromosomal localization and promoter analysis of the human transcription factor YY1. |journal=Nucleic Acids Res. |volume=26 |issue= 16 |pages= 3776–83 |year= 1998 |pmid= 9685495 |doi=PBB_Controls
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