YAF2

YY1 associated factor 2, also known as YAF2, is a human gene.cite web | title = Entrez Gene: YAF2 YY1 associated factor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10138| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.cite web | title = Entrez Gene: YAF2 YY1 associated factor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10138| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Mädge B, Geisen C, Möröy T, Schwab M |title=Yaf2 inhibits Myc biological function. |journal=Cancer Lett. |volume=193 |issue= 2 |pages= 171–6 |year= 2003 |pmid= 12706874 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ogawa H, Ishiguro K, Gaubatz S, "et al." |title=A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells. |journal=Science |volume=296 |issue= 5570 |pages= 1132–6 |year= 2002 |pmid= 12004135 |doi= 10.1126/science.1069861
*cite journal | author=Sawa C, Yoshikawa T, Matsuda-Suzuki F, "et al." |title=YEAF1/RYBP and YAF-2 are functionally distinct members of a cofactor family for the YY1 and E4TF1/hGABP transcription factors. |journal=J. Biol. Chem. |volume=277 |issue= 25 |pages= 22484–90 |year= 2002 |pmid= 11953439 |doi= 10.1074/jbc.M203060200
*cite journal | author=Bannasch D, Mädge B, Schwab M |title=Functional interaction of Yaf2 with the central region of MycN. |journal=Oncogene |volume=20 |issue= 41 |pages= 5913–9 |year= 2001 |pmid= 11593398 |doi= 10.1038/sj.onc.1204747
*cite journal | author=Kalenik JL, Chen D, Bradley ME, "et al." |title=Yeast two-hybrid cloning of a novel zinc finger protein that interacts with the multifunctional transcription factor YY1. |journal=Nucleic Acids Res. |volume=25 |issue= 4 |pages= 843–9 |year= 1997 |pmid= 9016636 |doi=

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