Mendelian Inheritance in Man
- Mendelian Inheritance in Man
The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and—when possible—links them to the relevant genes in the human genome and provides references for further research and tools for genomic analysis of a catalogued gene.
Versions
It is available as a book named after the project, and it is currently in its 12th edition. The online version is called Online Mendelian Inheritance in Man (OMIM), which can be accessed with the Entrez database searcher of the National Library of Medicine and is part of the NCBI Education project.
Collection process
The information in this database was collected and processed under the leadership of Dr. Victor A. McKusick at Johns Hopkins University, assisted by a team of science writers and editors. Relevant articles are identified, discussed and written up in the relevant entries in the MIM database.
The MIM code
Every disease and gene is assigned a six digit number of which the first number classifies the method of inheritance.
If the initial digit is 1, the trait is deemed autosomal dominant; if 2, autosomal recessive; if 3, X-linked. Wherever a trait defined in this dictionary has a MIM number, the number from the 12th edition of MIM, is given in square brackets with or without an asterisk (asterisks indicate that the mode of inheritance is known; a number symbol (#) before an entry number means that the phenotype can be caused by mutation in any of two or more genes) as appropriate e.g., Pelizaeus-Merzbacher disease [MIM*169500] is a well-established, autosomal, dominant, mendelian disorder.
ee also
* Medical classification
* Online Mendelian Inheritance in Animals
* Mouse Locus Catalogue
* Mendelian inheritance
* Comparative Toxicogenomics Database, a database that integrates chemicals and genes with human diseases, including OMIM data.
References
* Table from the [http://www.ncbi.nlm.nih.gov/Omim/omimfaq.html OMIM FAQ]
* cite book
last = McKusick
first = VA
title = Mendelian Inheritance in Man; A Catalog of Human Genes and Genetic Disorders
location = Baltimore, Maryland
publisher = The Johns Hopkins University Press
year = 1998
isbn = 0-8018-5742-2
External links
* [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM Online Mendelian Inheritance in Man] (to search OMIM)
Wikimedia Foundation.
2010.
Look at other dictionaries:
Mendelian Inheritance in Man — Héritage mendélien chez l Homme Le projet Héritage mendélien chez l Homme (en anglais Mendelian Inheritance in Man) est une base de données originellement compilée par Victor A. McKusick, et qui dresse un catalogue de toutes les maladies connues… … Wikipédia en Français
Mendelian Inheritance in Man — Das Online Mendelian Inheritance in Man (abgekürzt OMIM) ist eine Datenbank über die Gene des Menschen und deren Mutationen. Erbliche Erkrankungen sind dadurch sehr einfach identifizierbar. Die Datenbank enthält außerdem Informationen über… … Deutsch Wikipedia
Mendelian Inheritance in Man — A standard, comprehensive, regularly updated reference source for traits in humans that have been shown to be mendelian or that are thought on reasonable grounds to be so. Each entry has a six digit catalog number. Those securely established (by… … Medical dictionary
Online Mendelian Inheritance in Man — (OMIM) is a database that catalogues all the known diseases with a genetic component, and when possible links them to the relevant genes in the human genome and provides references for further research and tools for genomic analysis of a… … Wikipedia
Online Mendelian Inheritance in Man — (OMIM) ist eine Datenbank, in der Gene des Menschen und deren Mutationen erfasst sind. Erbliche Erkrankungen sind dadurch sehr einfach identifizierbar. Die Datenbank enthält außerdem Informationen über klinische Symptome, Erbgang,… … Deutsch Wikipedia
MIM-Catalogue [Mendelian Inheritance in Man] — MIM Catalogue [Mendelian Inheritance in Man]. Каталог фенетических маркеров у человека (т.е. фенотипов с классическим Менделевским наследованием), заложенный В.Мак Кьюсиком в 1966 (переиздавался в 1971, 1975, 1978, 1983, 1986, 1988 и 1990); с… … Молекулярная биология и генетика. Толковый словарь.
Mendelian inheritance — For a non technical introduction to the topic, see Introduction to genetics. Part of a series on Genetics Key components Chromosome DNA • RNA Genome Heredity … Wikipedia
Online Mendelian Inheritance in Animals — (OMIA) is an online database of genes, inherited disorders and traits in more than 135 animal species. It is modelled on, and is complementary to, Online Mendelian Inheritance in Man (OMIM). It aims to provide a publicly accessible catalogue of… … Wikipedia
List of Mendelian traits in humans — In Mendelian inheritance, a child receiving a dominant allele from either parent will have the dominant form of the trait. Only those that received the recessive allele from both parents present with the recessive phenotype. Purely Mendelian… … Wikipedia
MIM — • Mendelian Inheritance in Man; • message information model; • Multilateral Initiative in Malaria … Dictionary of medical acronyms & abbreviations
