MLX (gene)

MLX (gene)

MAX-like protein X, also known as MLX, is a human gene.cite web | title = Entrez Gene: MLX MAX-like protein X| url =| accessdate = ]

section_title =
summary_text = The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.cite web | title = Entrez Gene: MLX MAX-like protein X| url =| accessdate = ]


Further reading

citations =
*cite journal | author=Rommens JM, Durocher F, McArthur J, "et al." |title=Generation of a transcription map at the HSD17B locus centromeric to BRCA1 at 17q21. |journal=Genomics |volume=28 |issue= 3 |pages= 530–42 |year= 1996 |pmid= 7490091 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Hillier LD, Lennon G, Becker M, "et al." |title=Generation and analysis of 280,000 human expressed sequence tags. |journal=Genome Res. |volume=6 |issue= 9 |pages= 807–28 |year= 1997 |pmid= 8889549 |doi=
*cite journal | author=Bjerknes M, Cheng H |title=TCFL4: a gene at 17q21.1 encoding a putative basic helix-loop-helix leucine-zipper transcription factor. |journal=Gene |volume=181 |issue= 1-2 |pages= 7–11 |year= 1997 |pmid= 8973301 |doi=
*cite journal | author=Billin AN, Eilers AL, Queva C, Ayer DE |title=Mlx, a novel Max-like BHLHZip protein that interacts with the Max network of transcription factors. |journal=J. Biol. Chem. |volume=274 |issue= 51 |pages= 36344–50 |year= 2000 |pmid= 10593926 |doi=
*cite journal | author=Meroni G, Cairo S, Merla G, "et al." |title=Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway? |journal=Oncogene |volume=19 |issue= 29 |pages= 3266–77 |year= 2000 |pmid= 10918583 |doi= 10.1038/sj.onc.1203634
*cite journal | author=Billin AN, Eilers AL, Coulter KL, "et al." |title=MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network. |journal=Mol. Cell. Biol. |volume=20 |issue= 23 |pages= 8845–54 |year= 2000 |pmid= 11073985 |doi=
*cite journal | author=Cairo S, Merla G, Urbinati F, "et al." |title=WBSCR14, a gene mapping to the Williams--Beuren syndrome deleted region, is a new member of the Mlx transcription factor network. |journal=Hum. Mol. Genet. |volume=10 |issue= 6 |pages= 617–27 |year= 2001 |pmid= 11230181 |doi=
*cite journal | author=Eilers AL, Sundwall E, Lin M, "et al." |title=A novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex. |journal=Mol. Cell. Biol. |volume=22 |issue= 24 |pages= 8514–26 |year= 2003 |pmid= 12446771 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Merla G, Howald C, Antonarakis SE, Reymond A |title=The subcellular localization of the ChoRE-binding protein, encoded by the Williams-Beuren syndrome critical region gene 14, is regulated by 14-3-3. |journal=Hum. Mol. Genet. |volume=13 |issue= 14 |pages= 1505–14 |year= 2005 |pmid= 15163635 |doi= 10.1093/hmg/ddh163
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ma L, Tsatsos NG, Towle HC |title=Direct role of ChREBP.Mlx in regulating hepatic glucose-responsive genes. |journal=J. Biol. Chem. |volume=280 |issue= 12 |pages= 12019–27 |year= 2005 |pmid= 15664996 |doi= 10.1074/jbc.M413063200
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Sans CL, Satterwhite DJ, Stoltzman CA, "et al." |title=MondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysis. |journal=Mol. Cell. Biol. |volume=26 |issue= 13 |pages= 4863–71 |year= 2006 |pmid= 16782875 |doi= 10.1128/MCB.00657-05

External links


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