Apoptosis antagonizing transcription factor

Apoptosis antagonizing transcription factor

Apoptosis antagonizing transcription factor, also known as AATF, is a human gene.cite web | title = Entrez Gene: AATF apoptosis antagonizing transcription factor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26574| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.cite web | title = Entrez Gene: AATF apoptosis antagonizing transcription factor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26574| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Page G, Lödige I, Kögel D, Scheidtmann KH |title=AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis. |journal=FEBS Lett. |volume=462 |issue= 1-2 |pages= 187–91 |year= 2000 |pmid= 10580117 |doi=
*cite journal | author=Fanciulli M, Bruno T, Di Padova M, "et al." |title=Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb. |journal=FASEB J. |volume=14 |issue= 7 |pages= 904–12 |year= 2000 |pmid= 10783144 |doi=
*cite journal | author=Lindfors K, Halttunen T, Huotari P, "et al." |title=Identification of novel transcription factor-like gene from human intestinal cells. |journal=Biochem. Biophys. Res. Commun. |volume=276 |issue= 2 |pages= 660–6 |year= 2000 |pmid= 11027528 |doi= 10.1006/bbrc.2000.3480
*cite journal | author=Andersen JS, Lyon CE, Fox AH, "et al." |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=
*cite journal | author=Scherl A, Couté Y, Déon C, "et al." |title=Functional proteomic analysis of human nucleolus. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100–9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271
*cite journal | author=Bruno T, De Angelis R, De Nicola F, "et al." |title=Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb. |journal=Cancer Cell |volume=2 |issue= 5 |pages= 387–99 |year= 2003 |pmid= 12450794 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Di Padova M, Bruno T, De Nicola F, "et al." |title=Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter. |journal=J. Biol. Chem. |volume=278 |issue= 38 |pages= 36496–504 |year= 2003 |pmid= 12847090 |doi= 10.1074/jbc.M306694200
*cite journal | author=Guo Q, Xie J |title=AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4. |journal=J. Biol. Chem. |volume=279 |issue= 6 |pages= 4596–603 |year= 2004 |pmid= 14627703 |doi= 10.1074/jbc.M309811200
*cite journal | author=Barbato C, Corbi N, Canu N, "et al." |title=Rb binding protein Che-1 interacts with Tau in cerebellar granule neurons. Modulation during neuronal apoptosis. |journal=Mol. Cell. Neurosci. |volume=24 |issue= 4 |pages= 1038–50 |year= 2004 |pmid= 14697667 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Burgdorf S, Leister P, Scheidtmann KH |title=TSG101 interacts with apoptosis-antagonizing transcription factor and enhances androgen receptor-mediated transcription by promoting its monoubiquitination. |journal=J. Biol. Chem. |volume=279 |issue= 17 |pages= 17524–34 |year= 2004 |pmid= 14761944 |doi= 10.1074/jbc.M313703200
*cite journal | author=Xie J, Guo Q |title=AATF protects neural cells against oxidative damage induced by amyloid beta-peptide. |journal=Neurobiol. Dis. |volume=16 |issue= 1 |pages= 150–7 |year= 2004 |pmid= 15207272 |doi= 10.1016/j.nbd.2004.02.003
*cite journal | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Nousiainen M, Silljé HH, Sauer G, "et al." |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391–6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103
*cite journal | author=Kaul D, Mehrotra A |title=Functional characterization of AATF transcriptome in human leukemic cells. |journal=Mol. Cell. Biochem. |volume=297 |issue= 1-2 |pages= 215–20 |year= 2007 |pmid= 17006618 |doi= 10.1007/s11010-006-9317-1
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

External links

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