Heat shock factor

Heat shock factor

Pfam_box
Name = HSF-type DNA-binding
Symbol = HSF_DNA-bind


width = 300px
caption = Structure of the dimeric DNA binding domain of the yeast heat shock factor (cyan and green) bound to DNA (brown) based on PDB|3HTS.
Pfam= PF00447
InterPro= IPR000232
SMART=
PROSITE = PDOC00381
SCOP = 1hks
TCDB =
PDB = PDB2|1FBQ, PDB2|1FBS, PDB2|1FBU, PDB2|1FYK, PDB2|1FYL, PDB2|1FYM, PDB2|1HKS, PDB2|1HKT, PDB2|2HTS, PDB2|3HSF, PDB2|3HTSPfam_box
Name = Vertebrate heat shock transcription factor
Symbol = Vert_HS_TF


width =
caption =
Pfam= PF06546
InterPro= IPR010542
SMART=
PROSITE =
SCOP =
TCDB =
PDB =

Heat shock factor (HSF), in molecular biology, is the name given to transcription factors that regulate the expression of the heat shock proteins.cite journal | author = Sorger PK | title = Heat shock factor and the heat shock response | journal = Cell | volume = 65 | issue = 3 | pages = 363–6 | year = 1991 | month = May | pmid = 2018972 | doi = 10.1016/0092-8674(91)90452-5 | url = | issn = ] A typical example is the heat shock factor of Drosophila melanogaster.cite journal | author = Clos J, Westwood JT, Becker PB, Wilson S, Lambert K, Wu C | title = Molecular cloning and expression of a hexameric Drosophila heat shock factor subject to negative regulation | journal = Cell | volume = 63 | issue = 5 | pages = 1085–97 | year = 1990 | month = November | pmid = 2257625 | doi = 10.1016/0092-8674(90)90511-C | url = | issn = ]

Humans express the following heat shock factors:

References


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