USF1

Upstream transcription factor 1, also known as USF1, is a human gene.cite web | title = Entrez Gene: USF1 upstream transcription factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7391| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene.cite web | title = Entrez Gene: USF1 upstream transcription factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7391| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Corre S, Galibert MD |title= [USF as a key regulatory element of gene expression] |journal=Med Sci (Paris) |volume=22 |issue= 1 |pages= 62–7 |year= 2006 |pmid= 16386222 |doi=
*cite journal | author=Lee JC, Lusis AJ, Pajukanta P |title=Familial combined hyperlipidemia: upstream transcription factor 1 and beyond. |journal=Curr. Opin. Lipidol. |volume=17 |issue= 2 |pages= 101–9 |year= 2007 |pmid= 16531745 |doi= 10.1097/01.mol.0000217890.54875.13
*cite journal | author=Roy AL, Meisterernst M, Pognonec P, Roeder RG |title=Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF. |journal=Nature |volume=354 |issue= 6350 |pages= 245–8 |year= 1992 |pmid= 1961251 |doi= 10.1038/354245a0
*cite journal | author=Gregor PD, Sawadogo M, Roeder RG |title=The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer. |journal=Genes Dev. |volume=4 |issue= 10 |pages= 1730–40 |year= 1991 |pmid= 2249772 |doi=
*cite journal | author=Henrion AA, Martinez A, Mattei MG, "et al." |title=Structure, sequence, and chromosomal location of the gene for USF2 transcription factors in mouse. |journal=Genomics |volume=25 |issue= 1 |pages= 36–43 |year= 1995 |pmid= 7774954 |doi=
*cite journal | author=Ferré-D'Amaré AR, Pognonec P, Roeder RG, Burley SK |title=Structure and function of the b/HLH/Z domain of USF. |journal=EMBO J. |volume=13 |issue= 1 |pages= 180–9 |year= 1994 |pmid= 8306960 |doi=
*cite journal | author=Shieh BH, Sparkes RS, Gaynor RB, Lusis AJ |title=Localization of the gene-encoding upstream stimulatory factor (USF) to human chromosome 1q22-q23. |journal=Genomics |volume=16 |issue= 1 |pages= 266–8 |year= 1993 |pmid= 8486371 |doi= 10.1006/geno.1993.1174
*cite journal | author=Viollet B, Lefrançois-Martinez AM, Henrion A, "et al." |title=Immunochemical characterization and transacting properties of upstream stimulatory factor isoforms. |journal=J. Biol. Chem. |volume=271 |issue= 3 |pages= 1405–15 |year= 1996 |pmid= 8576131 |doi=
*cite journal | author=Ghosh AK, Datta PK, Jacob ST |title=The dual role of helix-loop--helix-zipper protein USF in ribosomal RNA gene transcription in vivo. |journal=Oncogene |volume=14 |issue= 5 |pages= 589–94 |year= 1997 |pmid= 9053857 |doi= 10.1038/sj.onc.1200866
*cite journal | author=Pognonec P, Boulukos KE, Aperlo C, "et al." |title=Cross-family interaction between the bHLHZip USF and bZip Fra1 proteins results in down-regulation of AP1 activity. |journal=Oncogene |volume=14 |issue= 17 |pages= 2091–8 |year= 1997 |pmid= 9160889 |doi= 10.1038/sj.onc.1201046
*cite journal | author=Roy AL, Du H, Gregor PD, "et al." |title=Cloning of an inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USF1. |journal=EMBO J. |volume=16 |issue= 23 |pages= 7091–104 |year= 1998 |pmid= 9384587 |doi= 10.1093/emboj/16.23.7091
*cite journal | author=Pajukanta P, Nuotio I, Terwilliger JD, "et al." |title=Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23. |journal=Nat. Genet. |volume=18 |issue= 4 |pages= 369–73 |year= 1998 |pmid= 9537421 |doi= 10.1038/ng0498-369
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Bengtsson SH, Madeyski-Bengtson K, Nilsson J, Bjursell G |title=Transcriptional regulation of the human carboxyl ester lipase gene in THP-1 monocytes: an E-box required for activation binds upstream stimulatory factors 1 and 2. |journal=Biochem. J. |volume=365 |issue= Pt 2 |pages= 481–8 |year= 2002 |pmid= 11945176 |doi= 10.1042/BJ20020223
*cite journal | author=Villavicencio EH, Yoon JW, Frank DJ, "et al." |title=Cooperative E-box regulation of human GLI1 by TWIST and USF. |journal=Genesis |volume=32 |issue= 4 |pages= 247–58 |year= 2002 |pmid= 11948912 |doi=
*cite journal | author=Coulson JM, Edgson JL, Marshall-Jones ZV, "et al." |title=Upstream stimulatory factor activates the vasopressin promoter via multiple motifs, including a non-canonical E-box. |journal=Biochem. J. |volume=369 |issue= Pt 3 |pages= 549–61 |year= 2003 |pmid= 12403649 |doi= 10.1042/BJ20021176
*cite journal | author=Salero E, Giménez C, Zafra F |title=Identification of a non-canonical E-box motif as a regulatory element in the proximal promoter region of the apolipoprotein E gene. |journal=Biochem. J. |volume=370 |issue= Pt 3 |pages= 979–86 |year= 2003 |pmid= 12444925 |doi= 10.1042/BJ20021142
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Pickwell GV, Shih H, Quattrochi LC |title=Interaction of upstream stimulatory factor proteins with an E-box located within the human CYP1A2 5'-flanking gene contributes to basal transcriptional gene activation. |journal=Biochem. Pharmacol. |volume=65 |issue= 7 |pages= 1087–96 |year= 2003 |pmid= 12663044 |doi=

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes