- FHL3
Four and a half LIM domains 3, also known as FHL3, is a human
gene .cite web | title = Entrez Gene: FHL3 four and a half LIM domains 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2275| accessdate = ]PBB_Summary
section_title =
summary_text = LIM proteins are defined by the possession of a highly conserved double zinc finger motif called the LIM domain. [supplied by OMIM] cite web | title = Entrez Gene: FHL3 four and a half LIM domains 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2275| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Morgan MJ, Madgwick AJ |title=Slim defines a novel family of LIM-proteins expressed in skeletal muscle. |journal=Biochem. Biophys. Res. Commun. |volume=225 |issue= 2 |pages= 632–8 |year= 1996 |pmid= 8753811 |doi= 10.1006/bbrc.1996.1222
*cite journal | author=Morgan MJ, Madgwick AJ |title=The LIM proteins FHL1 and FHL3 are expressed differently in skeletal muscle. |journal=Biochem. Biophys. Res. Commun. |volume=255 |issue= 2 |pages= 245–50 |year= 1999 |pmid= 10049693 |doi= 10.1006/bbrc.1999.0179
*cite journal | author=Lee SM, Tsui SK, Chan KK, "et al." |title=Chromosomal mapping of a skeletal muscle specific LIM-only protein FHL3 to the distal end of the short arm of human chromosome 1. |journal=Somat. Cell Mol. Genet. |volume=24 |issue= 3 |pages= 197–202 |year= 1999 |pmid= 10226657 |doi=
*cite journal | author=Li HY, Ng EK, Lee SM, "et al." |title=Protein-protein interaction of FHL3 with FHL2 and visualization of their interaction by green fluorescent proteins (GFP) two-fusion fluorescence resonance energy transfer (FRET). |journal=J. Cell. Biochem. |volume=80 |issue= 3 |pages= 293–303 |year= 2001 |pmid= 11135358 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Turner J, Nicholas H, Bishop D, "et al." |title=The LIM protein FHL3 binds basic Krüppel-like factor/Krüppel-like factor 3 and its co-repressor C-terminal-binding protein 2. |journal=J. Biol. Chem. |volume=278 |issue= 15 |pages= 12786–95 |year= 2003 |pmid= 12556451 |doi= 10.1074/jbc.M300587200
*cite journal | author=Mils V, Lee SM, Joly W, "et al." |title=LIM-only protein FHL3 interacts with CDC25B2 phosphatase. |journal=Exp. Cell Res. |volume=285 |issue= 1 |pages= 99–106 |year= 2003 |pmid= 12681290 |doi=
*cite journal | author=Coghill ID, Brown S, Cottle DL, "et al." |title=FHL3 is an actin-binding protein that regulates alpha-actinin-mediated actin bundling: FHL3 localizes to actin stress fibers and enhances cell spreading and stress fiber disassembly. |journal=J. Biol. Chem. |volume=278 |issue= 26 |pages= 24139–52 |year= 2003 |pmid= 12704194 |doi= 10.1074/jbc.M213259200
*cite journal | author=Purcell NH, Darwis D, Bueno OF, "et al." |title=Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes. |journal=Mol. Cell. Biol. |volume=24 |issue= 3 |pages= 1081–95 |year= 2004 |pmid= 14729955 |doi=
*cite journal | author=Samson T, Smyth N, Janetzky S, "et al." |title=The LIM-only proteins FHL2 and FHL3 interact with alpha- and beta-subunits of the muscle alpha7beta1 integrin receptor. |journal=J. Biol. Chem. |volume=279 |issue= 27 |pages= 28641–52 |year= 2004 |pmid= 15117962 |doi= 10.1074/jbc.M312894200
*cite journal | author=Takahashi K, Matsumoto C, Ra C |title=FHL3 negatively regulates human high-affinity IgE receptor beta-chain gene expression by acting as a transcriptional co-repressor of MZF-1. |journal=Biochem. J. |volume=386 |issue= Pt 1 |pages= 191–200 |year= 2005 |pmid= 15453830 |doi= 10.1042/BJ20040775
*cite journal | author=Philippar U, Schratt G, Dieterich C, "et al." |title=The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF. |journal=Mol. Cell |volume=16 |issue= 6 |pages= 867–80 |year= 2005 |pmid= 15610731 |doi= 10.1016/j.molcel.2004.11.039
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Cottle DL, McGrath MJ, Cowling BS, "et al." |title=FHL3 binds MyoD and negatively regulates myotube formation. |journal=J. Cell. Sci. |volume=120 |issue= Pt 8 |pages= 1423–35 |year= 2007 |pmid= 17389685 |doi= 10.1242/jcs.004739External links
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