ILF2

Interleukin enhancer binding factor 2, 45kDa, also known as ILF2, is a human gene.cite web | title = Entrez Gene: ILF2 interleukin enhancer binding factor 2, 45kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3608| accessdate = ]

PBB_Summary
section_title =
summary_text = Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of this gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression.cite web | title = Entrez Gene: ILF2 interleukin enhancer binding factor 2, 45kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3608| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kao PN, Chen L, Brock G, "et al." |title=Cloning and expression of cyclosporin A- and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90. |journal=J. Biol. Chem. |volume=269 |issue= 32 |pages= 20691–9 |year= 1994 |pmid= 7519613 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Marcoulatos P, Koussidis G, Mamuris Z, "et al." |title=Mapping interleukin enhancer binding factor 2 gene (ILF2) to human chromosome 1 (1q11-qter and 1p11-p12) by polymerase chain reaction amplification of human-rodent somatic cell hybrid DNA templates. |journal=J. Interferon Cytokine Res. |volume=16 |issue= 12 |pages= 1035–8 |year= 1997 |pmid= 8974006 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Ting NS, Kao PN, Chan DW, "et al." |title=DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45. |journal=J. Biol. Chem. |volume=273 |issue= 4 |pages= 2136–45 |year= 1998 |pmid= 9442054 |doi=
*cite journal | author=Langland JO, Kao PN, Jacobs BL |title=Nuclear factor-90 of activated T-cells: A double-stranded RNA-binding protein and substrate for the double-stranded RNA-dependent protein kinase, PKR. |journal=Biochemistry |volume=38 |issue= 19 |pages= 6361–8 |year= 1999 |pmid= 10320367 |doi= 10.1021/bi982410u
*cite journal | author=Satoh M, Shaheen VM, Kao PN, "et al." |title=Autoantibodies define a family of proteins with conserved double-stranded RNA-binding domains as well as DNA binding activity. |journal=J. Biol. Chem. |volume=274 |issue= 49 |pages= 34598–604 |year= 2000 |pmid= 10574923 |doi=
*cite journal | author=Ajuh P, Kuster B, Panov K, "et al." |title=Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. |journal=EMBO J. |volume=19 |issue= 23 |pages= 6569–81 |year= 2001 |pmid= 11101529 |doi= 10.1093/emboj/19.23.6569
*cite journal | author=Parker LM, Fierro-Monti I, Mathews MB |title=Nuclear factor 90 is a substrate and regulator of the eukaryotic initiation factor 2 kinase double-stranded RNA-activated protein kinase. |journal=J. Biol. Chem. |volume=276 |issue= 35 |pages= 32522–30 |year= 2001 |pmid= 11438540 |doi= 10.1074/jbc.M104408200
*cite journal | author=Reichman TW, Muñiz LC, Mathews MB |title=The RNA binding protein nuclear factor 90 functions as both a positive and negative regulator of gene expression in mammalian cells. |journal=Mol. Cell. Biol. |volume=22 |issue= 1 |pages= 343–56 |year= 2002 |pmid= 11739746 |doi=
*cite journal | author=Andersen JS, Lyon CE, Fox AH, "et al." |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=
*cite journal | author=Shin HJ, Kim SS, Cho YH, "et al." |title=Host cell proteins binding to the encapsidation signal epsilon in hepatitis B virus RNA. |journal=Arch. Virol. |volume=147 |issue= 3 |pages= 471–91 |year= 2002 |pmid= 11958450 |doi=
*cite journal | author=Scherl A, Couté Y, Déon C, "et al." |title=Functional proteomic analysis of human nucleolus. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100–9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Li J, Hawkins IC, Harvey CD, "et al." |title=Regulation of alternative splicing by SRrp86 and its interacting proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 21 |pages= 7437–47 |year= 2003 |pmid= 14559993 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Zhao G, Shi L, Qiu D, "et al." |title=NF45/ILF2 tissue expression, promoter analysis, and interleukin-2 transactivating function. |journal=Exp. Cell Res. |volume=305 |issue= 2 |pages= 312–23 |year= 2005 |pmid= 15817156 |doi= 10.1016/j.yexcr.2004.12.030
*cite journal | author=Nie Y, Ding L, Kao PN, "et al." |title=ADAR1 interacts with NF90 through double-stranded RNA and regulates NF90-mediated gene expression independently of RNA editing. |journal=Mol. Cell. Biol. |volume=25 |issue= 16 |pages= 6956–63 |year= 2005 |pmid= 16055709 |doi= 10.1128/MCB.25.16.6956-6963.2005
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

External links

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