KCNJ12

Potassium inwardly-rectifying channel, subfamily J, member 12, also known as KCNJ12 or K_ir2.2, is a human gene.cite web | title = Entrez Gene: KCNJ12 potassium inwardly-rectifying channel, subfamily J, member 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3768| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17.cite web | title = Entrez Gene: KCNJ12 potassium inwardly-rectifying channel, subfamily J, member 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3768| accessdate = ]

ee also

* Inward-rectifier potassium ion channel

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kubo Y, Adelman JP, Clapham DE, "et al." |title=International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 509–26 |year= 2006 |pmid= 16382105 |doi= 10.1124/pr.57.4.11
*cite journal | author=Mukherjee A, Varma SK, Natarajan K |title=Ankle joint instability in poliomyelitis. |journal=Indian journal of pediatrics |volume=39 |issue= 289 |pages= 37–8 |year= 1972 |pmid= 5024025 |doi=
*cite journal | author=Wible BA, De Biasi M, Majumder K, "et al." |title=Cloning and functional expression of an inwardly rectifying K+ channel from human atrium. |journal=Circ. Res. |volume=76 |issue= 3 |pages= 343–50 |year= 1995 |pmid= 7859381 |doi=
*cite journal | author=Namba N, Inagaki N, Gonoi T, "et al." |title=Kir2.2v: a possible negative regulator of the inwardly rectifying K+ channel Kir2.2. |journal=FEBS Lett. |volume=386 |issue= 2-3 |pages= 211–4 |year= 1996 |pmid= 8647284 |doi=
*cite journal | author=Hugnot JP, Pedeutour F, Le Calvez C, "et al." |title=The human inward rectifying K+ channel Kir 2.2 (KCNJ12) gene: gene structure, assignment to chromosome 17p11.1, and identification of a simple tandem repeat polymorphism. |journal=Genomics |volume=39 |issue= 1 |pages= 113–6 |year= 1997 |pmid= 9027495 |doi= 10.1006/geno.1996.4450
*cite journal | author=Gallagher PG, Forget BG |title=An alternate promoter directs expression of a truncated, muscle-specific isoform of the human ankyrin 1 gene. |journal=J. Biol. Chem. |volume=273 |issue= 3 |pages= 1339–48 |year= 1998 |pmid= 9430667 |doi=
*cite journal | author=Namba N, Mori R, Tanaka H, "et al." |title=The inwardly rectifying potassium channel subunit Kir2.2v (KCNJN1) maps to 17p11.2-->p11.1. |journal=Cytogenet. Cell Genet. |volume=79 |issue= 1-2 |pages= 85–7 |year= 1998 |pmid= 9533018 |doi=
*cite journal | author=Leonoudakis D, Mailliard W, Wingerd K, "et al." |title=Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97. |journal=J. Cell. Sci. |volume=114 |issue= Pt 5 |pages= 987–98 |year= 2001 |pmid= 11181181 |doi=
*cite journal | author=Preisig-Müller R, Schlichthörl G, Goerge T, "et al." |title=Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 11 |pages= 7774–9 |year= 2002 |pmid= 12032359 |doi= 10.1073/pnas.102609499
*cite journal | author=Chen L, Kawano T, Bajic S, "et al." |title=A glutamate residue at the C terminus regulates activity of inward rectifier K+ channels: implication for Andersen's syndrome. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 12 |pages= 8430–5 |year= 2002 |pmid= 12034888 |doi= 10.1073/pnas.122682899
*cite journal | author=Kaibara M, Ishihara K, Doi Y, "et al." |title=Identification of human Kir2.2 (KCNJ12) gene encoding functional inward rectifier potassium channel in both mammalian cells and Xenopus oocytes. |journal=FEBS Lett. |volume=531 |issue= 2 |pages= 250–4 |year= 2002 |pmid= 12417321 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Karkanis T, Li S, Pickering JG, Sims SM |title=Plasticity of KIR channels in human smooth muscle cells from internal thoracic artery. |journal=Am. J. Physiol. Heart Circ. Physiol. |volume=284 |issue= 6 |pages= H2325–34 |year= 2003 |pmid= 12598232 |doi= 10.1152/ajpheart.00559.2002
*cite journal | author=Stonehouse AH, Grubb BD, Pringle JH, "et al." |title=Nuclear immunostaining in rat neuronal cells using two anti-Kir2.2 ion channel polyclonal antibodies. |journal=J. Mol. Neurosci. |volume=20 |issue= 2 |pages= 189–94 |year= 2003 |pmid= 12794312 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Leonoudakis D, Conti LR, Radeke CM, "et al." |title=A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels. |journal=J. Biol. Chem. |volume=279 |issue= 18 |pages= 19051–63 |year= 2004 |pmid= 14960569 |doi= 10.1074/jbc.M400284200
*cite journal | author=Leonoudakis D, Conti LR, Anderson S, "et al." |title=Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins. |journal=J. Biol. Chem. |volume=279 |issue= 21 |pages= 22331–46 |year= 2004 |pmid= 15024025 |doi= 10.1074/jbc.M400285200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Fang Y, Schram G, Romanenko VG, "et al." |title=Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2. |journal=Am. J. Physiol., Cell Physiol. |volume=289 |issue= 5 |pages= C1134–44 |year= 2005 |pmid= 15958527 |doi= 10.1152/ajpcell.00077.2005
*cite journal | author=Kiesecker C, Zitron E, Scherer D, "et al." |title=Regulation of cardiac inwardly rectifying potassium current IK1 and Kir2.x channels by endothelin-1. |journal=J. Mol. Med. |volume=84 |issue= 1 |pages= 46–56 |year= 2006 |pmid= 16258766 |doi= 10.1007/s00109-005-0707-8

External links

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