[cite web | title = Entrez Gene: MYCL1 v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4610| accessdate = ] PBB_Summary]
section_title =
summary_text = MYCL1 is a bHLH (basic helix-loop-helix) transcription factor implicated in lung cancer. [cite journal |author=Ikegaki N, Minna J, Kennett RH |title=The human L-myc gene is expressed as two forms of protein in small cell lung carcinoma cell lines: detection by monoclonal antibodies specific to two myc homology box sequences |journal=EMBO J. |volume=8 |issue=6 |pages=1793–9 |year=1989 |pmid=2548855 |doi=] References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Lüscher B |title=Function and regulation of the transcription factors of the Myc/Max/Mad network. |journal=Gene |volume=277 |issue= 1-2 |pages= 1–14 |year= 2001 |pmid= 11602341 |doi=
*cite journal | author=Ikegaki N, Minna J, Kennett RH |title=The human L-myc gene is expressed as two forms of protein in small cell lung carcinoma cell lines: detection by monoclonal antibodies specific to two myc homology box sequences. |journal=EMBO J. |volume=8 |issue= 6 |pages= 1793–9 |year= 1989 |pmid= 2548855 |doi=
*cite journal | author=Kaye F, Battey J, Nau M, "et al." |title=Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing. |journal=Mol. Cell. Biol. |volume=8 |issue= 1 |pages= 186–95 |year= 1988 |pmid= 2827002 |doi=
*cite journal | author=De Greve J, Battey J, Fedorko J, "et al." |title=The human L-myc gene encodes multiple nuclear phosphoproteins from alternatively processed mRNAs. |journal=Mol. Cell. Biol. |volume=8 |issue= 10 |pages= 4381–8 |year= 1988 |pmid= 3054516 |doi=
*cite journal | author=DePinho RA, Hatton KS, Tesfaye A, "et al." |title=The human myc gene family: structure and activity of L-myc and an L-myc pseudogene. |journal=Genes Dev. |volume=1 |issue= 10 |pages= 1311–26 |year= 1988 |pmid= 3322939 |doi=
*cite journal | author=Atchley WR, Fitch WM |title=Myc and Max: molecular evolution of a family of proto-oncogene products and their dimerization partner. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue= 22 |pages= 10217–21 |year= 1995 |pmid= 7479755 |doi=
*cite journal | author=Speleman F, Van Camp G, Van Roy N |title=Reassignment of MYCL1 to human chromosome 1p34.3 by fluorescence in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=72 |issue= 2-3 |pages= 189–90 |year= 1997 |pmid= 8978772 |doi=
*cite journal | author=FitzGerald MJ, Arsura M, Bellas RE, "et al." |title=Differential effects of the widely expressed dMax splice variant of Max on E-box vs initiator element-mediated regulation by c-Myc. |journal=Oncogene |volume=18 |issue= 15 |pages= 2489–98 |year= 1999 |pmid= 10229200 |doi= 10.1038/sj.onc.1202611
*cite journal | author=Kumimoto H, Hamajima N, Nishimoto Y, "et al." |title=L-myc genotype is associated with different susceptibility to lung cancer in smokers. |journal=Jpn. J. Cancer Res. |volume=93 |issue= 1 |pages= 1–5 |year= 2002 |pmid= 11802801 |doi=
*cite journal | author=Suzuki H, Yamashiro K |title=L-myc restriction fragment length polymorphism and histological pattern of invasion in lung adenocarcinoma. |journal=Oncol. Rep. |volume=9 |issue= 2 |pages= 345–7 |year= 2002 |pmid= 11836605 |doi=
*cite journal | author=Primdahl H, von der Maase H, Christensen M, "et al." |title=Allelic deletions of Rb and L-myc in urine sediments from patients with bladder tumors or carcinoma in situ. |journal=Oncol. Rep. |volume=9 |issue= 3 |pages= 551–5 |year= 2002 |pmid= 11956626 |doi=
*cite journal | author=Demopoulos K, Arvanitis DA, Vassilakis DA, "et al." |title=MYCL1, FHIT, SPARC, p16(INK4) and TP53 genes associated to lung cancer in idiopathic pulmonary fibrosis. |journal=J. Cell. Mol. Med. |volume=6 |issue= 2 |pages= 215–22 |year= 2003 |pmid= 12169206 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Wu R, Lin L, Beer DG, "et al." |title=Amplification and overexpression of the L-MYC proto-oncogene in ovarian carcinomas. |journal=Am. J. Pathol. |volume=162 |issue= 5 |pages= 1603–10 |year= 2003 |pmid= 12707044 |doi=
*cite journal | author=Kambara T, Sharp GB, Nagasaka T, "et al." |title=Allelic loss of a common microsatellite marker MYCL1: a useful prognostic factor of poor outcomes in colorectal cancer. |journal=Clin. Cancer Res. |volume=10 |issue= 5 |pages= 1758–63 |year= 2004 |pmid= 15014029 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Spinola M, Falvella FS, Galvan A, "et al." |title=Ethnic differences in frequencies of gene polymorphisms in the MYCL1 region and modulation of lung cancer patients' survival. |journal=Lung Cancer |volume=55 |issue= 3 |pages= 271–7 |year= 2007 |pmid= 17145094 |doi= 10.1016/j.lungcan.2006.10.023
External links
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