ID3 (gene)

ID3 (gene)

Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein, also known as ID3, is a human gene.cite web | title = Entrez Gene: ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3399| accessdate = ]

PBB_Summary
section_title =
summary_text = Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA. [supplied by OMIM] cite web | title = Entrez Gene: ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3399| accessdate = ]

See also

* Inhibitor of DNA-binding protein

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Ellmeier W, Aguzzi A, Kleiner E, "et al." |title=Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development. |journal=EMBO J. |volume=11 |issue= 7 |pages= 2563–71 |year= 1992 |pmid= 1628620 |doi=
*cite journal | author=White PS, Maris JM, Beltinger C, "et al." |title=A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue= 12 |pages= 5520–4 |year= 1995 |pmid= 7777541 |doi=
*cite journal | author=Kato S, Sekine S, Oh SW, "et al." |title=Construction of a human full-length cDNA bank. |journal=Gene |volume=150 |issue= 2 |pages= 243–50 |year= 1995 |pmid= 7821789 |doi=
*cite journal | author=Deed RW, Hirose T, Mitchell EL, "et al." |title=Structural organisation and chromosomal mapping of the human Id-3 gene. |journal=Gene |volume=151 |issue= 1-2 |pages= 309–14 |year= 1995 |pmid= 7828896 |doi=
*cite journal | author=Deed RW, Bianchi SM, Atherton GT, "et al." |title=An immediate early human gene encodes an Id-like helix-loop-helix protein and is regulated by protein kinase C activation in diverse cell types. |journal=Oncogene |volume=8 |issue= 3 |pages= 599–607 |year= 1993 |pmid= 8437843 |doi=
*cite journal | author=Ishiguro A, Spirin K, Shiohara M, "et al." |title=Expression of Id2 and Id3 mRNA in human lymphocytes. |journal=Leuk. Res. |volume=19 |issue= 12 |pages= 989–96 |year= 1996 |pmid= 8632670 |doi=
*cite journal | author=Wibley J, Deed R, Jasiok M, "et al." |title=A homology model of the Id-3 helix-loop-helix domain as a basis for structure-function predictions. |journal=Biochim. Biophys. Acta |volume=1294 |issue= 2 |pages= 138–46 |year= 1996 |pmid= 8645731 |doi=
*cite journal | author=Loveys DA, Streiff MB, Kato GJ |title=E2A basic-helix-loop-helix transcription factors are negatively regulated by serum growth factors and by the Id3 protein. |journal=Nucleic Acids Res. |volume=24 |issue= 14 |pages= 2813–20 |year= 1996 |pmid= 8759016 |doi=
*cite journal | author=Deed RW, Armitage S, Norton JD |title=Nuclear localization and regulation of Id protein through an E protein-mediated chaperone mechanism. |journal=J. Biol. Chem. |volume=271 |issue= 39 |pages= 23603–6 |year= 1996 |pmid= 8798572 |doi=
*cite journal | author=Deed RW, Jasiok M, Norton JD |title=Attenuated function of a variant form of the helix-loop-helix protein, Id-3, generated by an alternative splicing mechanism. |journal=FEBS Lett. |volume=393 |issue= 1 |pages= 113–6 |year= 1996 |pmid= 8804437 |doi=
*cite journal | author=Chen B, Lim RW |title=Physical and functional interactions between the transcriptional inhibitors Id3 and ITF-2b. Evidence toward a novel mechanism regulating muscle-specific gene expression. |journal=J. Biol. Chem. |volume=272 |issue= 4 |pages= 2459–63 |year= 1997 |pmid= 8999959 |doi=
*cite journal | author=Langlands K, Yin X, Anand G, Prochownik EV |title=Differential interactions of Id proteins with basic-helix-loop-helix transcription factors. |journal=J. Biol. Chem. |volume=272 |issue= 32 |pages= 19785–93 |year= 1997 |pmid= 9242638 |doi=
*cite journal | author=Deed RW, Hara E, Atherton GT, "et al." |title=Regulation of Id3 cell cycle function by Cdk-2-dependent phosphorylation. |journal=Mol. Cell. Biol. |volume=17 |issue= 12 |pages= 6815–21 |year= 1997 |pmid= 9372912 |doi=
*cite journal | author=Deed RW, Jasiok M, Norton JD |title=Lymphoid-specific expression of the Id3 gene in hematopoietic cells. Selective antagonism of E2A basic helix-loop-helix protein associated with Id3-induced differentiation of erythroleukemia cells. |journal=J. Biol. Chem. |volume=273 |issue= 14 |pages= 8278–86 |year= 1998 |pmid= 9525934 |doi=
*cite journal | author=Asp J, Thornemo M, Inerot S, Lindahl A |title=The helix-loop-helix transcription factors Id1 and Id3 have a functional role in control of cell division in human normal and neoplastic chondrocytes. |journal=FEBS Lett. |volume=438 |issue= 1-2 |pages= 85–90 |year= 1998 |pmid= 9821964 |doi=
*cite journal | author=Yates PR, Atherton GT, Deed RW, "et al." |title=Id helix-loop-helix proteins inhibit nucleoprotein complex formation by the TCF ETS-domain transcription factors. |journal=EMBO J. |volume=18 |issue= 4 |pages= 968–76 |year= 1999 |pmid= 10022839 |doi= 10.1093/emboj/18.4.968
*cite journal | author=Moldes M, Boizard M, Liepvre XL, "et al." |title=Functional antagonism between inhibitor of DNA binding (Id) and adipocyte determination and differentiation factor 1/sterol regulatory element-binding protein-1c (ADD1/SREBP-1c) trans-factors for the regulation of fatty acid synthase promoter in adipocytes. |journal=Biochem. J. |volume=344 Pt 3 |issue= |pages= 873–80 |year= 2000 |pmid= 10585876 |doi=
*cite journal | author=Bounpheng MA, Dimas JJ, Dodds SG, Christy BA |title=Degradation of Id proteins by the ubiquitin-proteasome pathway. |journal=FASEB J. |volume=13 |issue= 15 |pages= 2257–64 |year= 2000 |pmid= 10593873 |doi=
*cite journal | author=Suzuki H, Fukunishi Y, Kagawa I, "et al." |title=Protein-protein interaction panel using mouse full-length cDNAs. |journal=Genome Res. |volume=11 |issue= 10 |pages= 1758–65 |year= 2001 |pmid= 11591653 |doi= 10.1101/gr.180101
*cite journal | author=Jögi A, Persson P, Grynfeld A, "et al." |title=Modulation of basic helix-loop-helix transcription complex formation by Id proteins during neuronal differentiation. |journal=J. Biol. Chem. |volume=277 |issue= 11 |pages= 9118–26 |year= 2002 |pmid= 11756408 |doi= 10.1074/jbc.M107713200

External links

*

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