Transcription Factor II E
- Transcription Factor II E
protein
Name = general transcription factor IIE, polypeptide 1, alpha 56kDa
caption =
width =
HGNCid = 4650
Symbol = GTF2E1
AltSymbols = TF2E1
EntrezGene = 2960
OMIM = 189962
RefSeq = NM_005513
UniProt = P29083
PDB =
ECnumber =
Chromosome = 3
Arm = q
Band = 21
LocusSupplementaryData = -q24protein
Name = general transcription factor IIE, polypeptide 2, beta 34kDa
caption =
width =
HGNCid = 4651
Symbol = GTF2E2
AltSymbols = TF2E2
EntrezGene = 2961
OMIM = 189964
RefSeq = NM_002095
UniProt = P29084
PDB =
ECnumber =
Chromosome = 8
Arm = p
Band = 12
LocusSupplementaryData =
Transcription Factor II E (TFIIE) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.[cite book | author = Lewin, Benjamin | title = Genes VIII | publisher = Pearson Prentice Hall | location = Upper Saddle River, NJ | year = 2004 | pages = p636-637 | isbn = 0-13-144946-X | oclc = | doi = ] ]Transcription Factor II E is encoded by the gene|GTF2E1 and gene|GTF2E2 genes.[cite journal | author = Ohkuma Y, Hashimoto S, Roeder RG, Horikoshi M | title = Identification of two large subdomains in TFIIE-alpha on the basis of homology between Xenopus and human sequences | journal = Nucleic Acids Res. | volume = 20 | issue = 21 | pages = 5838 | year = 1992 | pmid = 1454543 | doi = | issn = ] ][cite journal | author = Heng HH, Xiao H, Shi XM, Greenblatt J, Tsui LC | title = Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome | journal = Hum. Mol. Genet. | volume = 3 | issue = 1 | pages = 61–4 | year = 1994 | pmid = 8162052 | doi = | issn = ] ][cite journal | author = Sumimoto H, Ohkuma Y, Sinn E, Kato H, Shimasaki S, Horikoshi M, Roeder RG | title = Conserved sequence motifs in the small subunit of human general transcription factor TFIIE | journal = Nature | volume = 354 | issue = 6352 | pages = 401–4 | year = 1991 | pmid = 1956404 | doi = 10.1038/354401a0 | issn = ] TFIIE is thought to be involved in DNA melting at the promoter: it contains a zinc ribbon motif that can bind single stranded DNA.][cite journal | author = Lee TI, Young RA | title = Transcription of eukaryotic protein-coding genes | journal = Annu. Rev. Genet. | volume = 34 | issue = | pages = 77–137 | year = 2000 | pmid = 11092823 | doi = 10.1146/annurev.genet.34.1.77] ] See also
* TFIIA
* TFIIB
* TFIID
References
External links
*
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2010.
Look at other dictionaries:
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transcription factor — ▪ biology molecule that controls the activity of a gene by determining whether the gene s DNA (deoxyribonucleic acid) is transcribed into RNA (ribonucleic acid). The enzyme RNA polymerase catalyzes the chemical reactions that synthesize RNA … Universalium
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transcription factor — Protein required for recognition by RNA polymerases of specific stimulatory sequences in eukaryotic genes. Several are known that activate transcription by RNA polymerase II when bound to upstream promoters. Transcription of the 5S RNA gene in… … Dictionary of molecular biology
transcription factor — noun Date: 1972 any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription … New Collegiate Dictionary
