HOXA4

Homeobox A4, also known as HOXA4, is a human gene.cite web | title = Entrez Gene: HOXA4 homeobox A4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3201| accessdate = ]

PBB_Summary
section_title =
summary_text = In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.cite web | title = Entrez Gene: HOXA4 homeobox A4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3201| accessdate = ]

ee also

* Homeobox

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Scott MP |title=Vertebrate homeobox gene nomenclature. |journal=Cell |volume=71 |issue= 4 |pages= 551–3 |year= 1992 |pmid= 1358459 |doi=
*cite journal | author=Buettner R, Yim SO, Hong YS, "et al." |title=Alteration of homeobox gene expression by N-ras transformation of PA-1 human teratocarcinoma cells. |journal=Mol. Cell. Biol. |volume=11 |issue= 7 |pages= 3573–83 |year= 1991 |pmid= 1675427 |doi=
*cite journal | author=McAlpine PJ, Shows TB |title=Nomenclature for human homeobox genes. |journal=Genomics |volume=7 |issue= 3 |pages= 460 |year= 1990 |pmid= 1973146 |doi=
*cite journal | author=Peverali FA, D'Esposito M, Acampora D, "et al." |title=Expression of HOX homeogenes in human neuroblastoma cell culture lines. |journal=Differentiation |volume=45 |issue= 1 |pages= 61–9 |year= 1991 |pmid= 1981366 |doi=
*cite journal | author=Ferguson-Smith AC, Fienberg A, Ruddle FH |title=Isolation, chromosomal localization, and nucleotide sequence of the human HOX 1.4 homeobox. |journal=Genomics |volume=5 |issue= 2 |pages= 250–8 |year= 1989 |pmid= 2571574 |doi=
*cite journal | author=Boncinelli E, Acampora D, Pannese M, "et al." |title=Organization of human class I homeobox genes. |journal=Genome |volume=31 |issue= 2 |pages= 745–56 |year= 1990 |pmid= 2576652 |doi=
*cite journal | author=Verlinsky Y, Morozov G, Gindilis V, "et al." |title=Homeobox gene expression in human oocytes and preembryos. |journal=Mol. Reprod. Dev. |volume=41 |issue= 2 |pages= 127–32 |year= 1995 |pmid= 7654365 |doi= 10.1002/mrd.1080410202
*cite journal | author=Apiou F, Flagiello D, Cillo C, "et al." |title=Fine mapping of human HOX gene clusters. |journal=Cytogenet. Cell Genet. |volume=73 |issue= 1-2 |pages= 114–5 |year= 1996 |pmid= 8646877 |doi=
*cite journal | author=Kuliev A, Kukharenko V, Morozov G, "et al." |title=Expression of homebox-containing genes in human preimplantation development and in embryos with chromosomal aneuploidies. |journal=J. Assist. Reprod. Genet. |volume=13 |issue= 2 |pages= 177–81 |year= 1996 |pmid= 8688592 |doi=
*cite journal | author=Duluc I, Lorentz O, Fritsch C, "et al." |title=Changing intestinal connective tissue interactions alters homeobox gene expression in epithelial cells. |journal=J. Cell. Sci. |volume=110 ( Pt 11) |issue= |pages= 1317–24 |year= 1997 |pmid= 9202392 |doi=
*cite journal | author=Stelnicki EJ, Kömüves LG, Kwong AO, "et al." |title=HOX homeobox genes exhibit spatial and temporal changes in expression during human skin development. |journal=J. Invest. Dermatol. |volume=110 |issue= 2 |pages= 110–5 |year= 1998 |pmid= 9457903 |doi= 10.1046/j.1523-1747.1998.00092.x
*cite journal | author=Verlinsky Y, Morozov G, Verlinsky O, "et al." |title=Isolation of cDNA libraries from individual human preimplantation embryos. |journal=Mol. Hum. Reprod. |volume=4 |issue= 6 |pages= 571–5 |year= 1998 |pmid= 9665340 |doi=
*cite journal | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi=
*cite journal | author=Kosaki K, Kosaki R, Suzuki T, "et al." |title=Complete mutation analysis panel of the 39 human HOX genes. |journal=Teratology |volume=65 |issue= 2 |pages= 50–62 |year= 2002 |pmid= 11857506 |doi= 10.1002/tera.10009
*cite journal | author=Larramendy ML, Niini T, Elonen E, "et al." |title=Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis. |journal=Haematologica |volume=87 |issue= 6 |pages= 569–77 |year= 2003 |pmid= 12031912 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Méchine-Neuville A, Lefebvre O, Bellocq JP, "et al." |title= [Increased expression of HOXA9 gene in Hirschsprung disease] |journal=Gastroenterol. Clin. Biol. |volume=26 |issue= 12 |pages= 1110–7 |year= 2003 |pmid= 12520199 |doi=
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Strathdee G, Sim A, Parker A, "et al." |title=Promoter hypermethylation silences expression of the HoxA4 gene and correlates with IgVh mutational status in CLL. |journal=Leukemia |volume=20 |issue= 7 |pages= 1326–9 |year= 2007 |pmid= 16688227 |doi= 10.1038/sj.leu.2404254

External links

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