HMGN1

High-mobility group nucleosome binding domain 1, also known as HMGN1, is a human gene.cite web | title = Entrez Gene: HMGN1 high-mobility group nucleosome binding domain 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3150| accessdate = ]

PBB_Summary
section_title =
summary_text = Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function. [supplied by OMIM] cite web | title = Entrez Gene: HMGN1 high-mobility group nucleosome binding domain 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3150| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Pash J, Popescu N, Matocha M, "et al." |title=Chromosomal protein HMG-14 gene maps to the Down syndrome region of human chromosome 21 and is overexpressed in mouse trisomy 16. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=87 |issue= 10 |pages= 3836–40 |year= 1990 |pmid= 2140193 |doi=
*cite journal | author=Landsman D, McBride OW, Soares N, "et al." |title=Chromosomal protein HMG-14. Identification, characterization, and chromosome localization of a functional gene from the large human multigene family. |journal=J. Biol. Chem. |volume=264 |issue= 6 |pages= 3421–7 |year= 1989 |pmid= 2563381 |doi=
*cite journal | author=Landsman D, Srikantha T, Westermann R, Bustin M |title=Chromosomal protein HMG-14. Complete human cDNA sequence and evidence for a multigene family. |journal=J. Biol. Chem. |volume=261 |issue= 34 |pages= 16082–6 |year= 1987 |pmid= 3782107 |doi=
*cite journal | author=Leffak M, Trempe JP |title=Histone H1 and HMG 14/17 are deposited nonrandomly in the nucleus. |journal=Nucleic Acids Res. |volume=13 |issue= 13 |pages= 4853–69 |year= 1985 |pmid= 4022776 |doi=
*cite journal | author=Postnikov YV, Trieschmann L, Rickers A, Bustin M |title=Homodimers of chromosomal proteins HMG-14 and HMG-17 in nucleosome cores. |journal=J. Mol. Biol. |volume=252 |issue= 4 |pages= 423–32 |year= 1995 |pmid= 7563062 |doi= 10.1006/jmbi.1995.0508
*cite journal | author=Ding HF, Rimsky S, Batson SC, "et al." |title=Stimulation of RNA polymerase II elongation by chromosomal protein HMG-14. |journal=Science |volume=265 |issue= 5173 |pages= 796–9 |year= 1994 |pmid= 8047885 |doi=
*cite journal | author=Pash JM, Alfonso PJ, Bustin M |title=Aberrant expression of high mobility group chromosomal protein 14 affects cellular differentiation. |journal=J. Biol. Chem. |volume=268 |issue= 18 |pages= 13632–8 |year= 1993 |pmid= 8514795 |doi=
*cite journal | author=Bustin M, Alfonso PJ, Pash JM, "et al." |title=Characterization of transgenic mice with an increased content of chromosomal protein HMG-14 in their chromatin. |journal=DNA Cell Biol. |volume=14 |issue= 12 |pages= 997–1005 |year= 1996 |pmid= 8534374 |doi=
*cite journal | author=Hock R, Scheer U, Bustin M |title=Chromosomal proteins HMG-14 and HMG-17 are released from mitotic chromosomes and imported into the nucleus by active transport. |journal=J. Cell Biol. |volume=143 |issue= 6 |pages= 1427–36 |year= 1999 |pmid= 9852141 |doi=
*cite journal | author=Louie DF, Gloor KK, Galasinski SC, "et al." |title=Phosphorylation and subcellular redistribution of high mobility group proteins 14 and 17, analyzed by mass spectrometry. |journal=Protein Sci. |volume=9 |issue= 1 |pages= 170–9 |year= 2000 |pmid= 10739259 |doi=
*cite journal | author=Bergel M, Herrera JE, Thatcher BJ, "et al." |title=Acetylation of novel sites in the nucleosomal binding domain of chromosomal protein HMG-14 by p300 alters its interaction with nucleosomes. |journal=J. Biol. Chem. |volume=275 |issue= 15 |pages= 11514–20 |year= 2000 |pmid= 10753971 |doi=
*cite journal | author=Hattori M, Fujiyama A, Taylor TD, "et al." |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518
*cite journal | author=Prymakowska-Bosak M, Misteli T, Herrera JE, "et al." |title=Mitotic phosphorylation prevents the binding of HMGN proteins to chromatin. |journal=Mol. Cell. Biol. |volume=21 |issue= 15 |pages= 5169–78 |year= 2001 |pmid= 11438671 |doi= 10.1128/MCB.21.15.5169-5178.2001
*cite journal | author=Prymakowska-Bosak M, Hock R, Catez F, "et al." |title=Mitotic phosphorylation of chromosomal protein HMGN1 inhibits nuclear import and promotes interaction with 14.3.3 proteins. |journal=Mol. Cell. Biol. |volume=22 |issue= 19 |pages= 6809–19 |year= 2002 |pmid= 12215538 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Soloaga A, Thomson S, Wiggin GR, "et al." |title=MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14. |journal=EMBO J. |volume=22 |issue= 11 |pages= 2788–97 |year= 2003 |pmid= 12773393 |doi= 10.1093/emboj/cdg273
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Zou Y, Jiang X, Wang Y |title=Identification of novel in vivo phosphorylation sites in high mobility group N1 protein from the MCF-7 human breast cancer cells. |journal=Biochemistry |volume=43 |issue= 20 |pages= 6322–9 |year= 2004 |pmid= 15147216 |doi= 10.1021/bi0362828
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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