SOX6

SRY (sex determining region Y)-box 6, also known as SOX6, is a human gene.cite web | title = Entrez Gene: SOX6 SRY (sex determining region Y)-box 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55553| accessdate = ]

PBB_Summary
section_title =
summary_text = The SOX gene family encodes a group of transcription factors defined by the conserved high mobility group (HMG) DNA-binding domain. Unlike most transcription factors, SOX transcription factors bind to the minor groove of DNA, causing a 70- to 85-degree bend and introducing local conformational changes. [supplied by OMIM] cite web | title = Entrez Gene: SOX6 SRY (sex determining region Y)-box 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55553| accessdate = ]

ee also

* SOX genes

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Denny P, Swift S, Brand N, "et al." |title=A conserved family of genes related to the testis determining gene, SRY. |journal=Nucleic Acids Res. |volume=20 |issue= 11 |pages= 2887 |year= 1992 |pmid= 1614875 |doi=
*cite journal | author=Lefebvre V, Li P, de Crombrugghe B |title=A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. |journal=EMBO J. |volume=17 |issue= 19 |pages= 5718–33 |year= 1998 |pmid= 9755172 |doi= 10.1093/emboj/17.19.5718
*cite journal | author=Hagiwara N, Klewer SE, Samson RA, "et al." |title=Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 8 |pages= 4180–5 |year= 2000 |pmid= 10760285 |doi=
*cite journal | author=Yamashita A, Ito M, Takamatsu N, Shiba T |title=Characterization of Solt, a novel SoxLZ/Sox6 binding protein expressed in adult mouse testis. |journal=FEBS Lett. |volume=481 |issue= 2 |pages= 147–51 |year= 2000 |pmid= 10996314 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Cohen-Barak O, Hagiwara N, Arlt MF, "et al." |title=Cloning, characterization and chromosome mapping of the human SOX6 gene. |journal=Gene |volume=265 |issue= 1-2 |pages= 157–64 |year= 2001 |pmid= 11255018 |doi=
*cite journal | author=Murakami A, Ishida S, Thurlow J, "et al." |title=SOX6 binds CtBP2 to repress transcription from the Fgf-3 promoter. |journal=Nucleic Acids Res. |volume=29 |issue= 16 |pages= 3347–55 |year= 2001 |pmid= 11504872 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Cohen-Barak O, Yi Z, Hagiwara N, "et al." |title=Sox6 regulation of cardiac myocyte development. |journal=Nucleic Acids Res. |volume=31 |issue= 20 |pages= 5941–8 |year= 2004 |pmid= 14530442 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Ueda R, Yoshida K, Kawakami Y, "et al." |title=Expression of a transcriptional factor, SOX6, in human gliomas. |journal=Brain tumor pathology |volume=21 |issue= 1 |pages= 35–8 |year= 2005 |pmid= 15696967 |doi=
*cite journal | author=Ueda R, Yoshida K, Kawakami Y, "et al." |title=Immunohistochemical analysis of SOX6 expression in human brain tumors. |journal=Brain tumor pathology |volume=21 |issue= 3 |pages= 117–20 |year= 2005 |pmid= 15696972 |doi=
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139
*cite journal | author=Fernández-Lloris R, Osses N, Jaffray E, "et al." |title=Repression of SOX6 transcriptional activity by SUMO modification. |journal=FEBS Lett. |volume=580 |issue= 5 |pages= 1215–21 |year= 2006 |pmid= 16442531 |doi= 10.1016/j.febslet.2006.01.031
*cite journal | author=Ikeda T, Saito T, Ushita M, "et al." |title=Identification and characterization of the human SOX6 promoter. |journal=Biochem. Biophys. Res. Commun. |volume=357 |issue= 2 |pages= 383–90 |year= 2007 |pmid= 17433257 |doi= 10.1016/j.bbrc.2007.03.133

External links

*

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes