FLI1

Friend leukemia virus integration 1, also known as FLI1, is a human gene.

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Further reading

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*cite journal | author=Ban J, Siligan C, Kreppel M, "et al." |title=EWS-FLI1 in Ewing's sarcoma: real targets and collateral damage. |journal=Adv. Exp. Med. Biol. |volume=587 |issue= |pages= 41–52 |year= 2007 |pmid= 17163154 |doi=
*cite journal | author=Prasad DD, Rao VN, Reddy ES |title=Structure and expression of human Fli-1 gene. |journal=Cancer Res. |volume=52 |issue= 20 |pages= 5833–7 |year= 1992 |pmid= 1394211 |doi=
*cite journal | author=Watson DK, Smyth FE, Thompson DM, "et al." |title=The ERGB/Fli-1 gene: isolation and characterization of a new member of the family of human ETS transcription factors. |journal=Cell Growth Differ. |volume=3 |issue= 10 |pages= 705–13 |year= 1992 |pmid= 1445800 |doi=
*cite journal | author=Delattre O, Zucman J, Plougastel B, "et al." |title=Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. |journal=Nature |volume=359 |issue= 6391 |pages= 162–5 |year= 1992 |pmid= 1522903 |doi= 10.1038/359162a0
*cite journal | author=Baud V, Lipinski M, Rassart E, "et al." |title=The human homolog of the mouse common viral integration region, FLI1, maps to 11q23-q24. |journal=Genomics |volume=11 |issue= 1 |pages= 223–4 |year= 1992 |pmid= 1765382 |doi=
*cite journal | author=Bergeron D, Poliquin L, Kozak CA, Rassart E |title=Identification of a common viral integration region in Cas-Br-E murine leukemia virus-induced non-T-, non-B-cell lymphomas. |journal=J. Virol. |volume=65 |issue= 1 |pages= 7–15 |year= 1991 |pmid= 1845910 |doi=
*cite journal | author=Bhagirath T, Abe S, Nojima T, Yoshida MC |title=Molecular analysis of a t(11;22) translocation junction in a case of Ewing's sarcoma. |journal=Genes Chromosomes Cancer |volume=13 |issue= 2 |pages= 126–32 |year= 1995 |pmid= 7542907 |doi=
*cite journal | author=Liang H, Mao X, Olejniczak ET, "et al." |title=Solution structure of the ets domain of Fli-1 when bound to DNA. |journal=Nat. Struct. Biol. |volume=1 |issue= 12 |pages= 871–5 |year= 1995 |pmid= 7773776 |doi=
*cite journal | author=May WA, Lessnick SL, Braun BS, "et al." |title=The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1. |journal=Mol. Cell. Biol. |volume=13 |issue= 12 |pages= 7393–8 |year= 1994 |pmid= 8246959 |doi=
*cite journal | author=Hromas R, May W, Denny C, "et al." |title=Human FLI-1 localizes to chromosome 11Q24 and has an aberrant transcript in neuroepithelioma. |journal=Biochim. Biophys. Acta |volume=1172 |issue= 1-2 |pages= 155–8 |year= 1993 |pmid= 8439553 |doi=
*cite journal | author=Magnaghi-Jaulin L, Masutani H, Robin P, "et al." |title=SRE elements are binding sites for the fusion protein EWS-FLI-1. |journal=Nucleic Acids Res. |volume=24 |issue= 6 |pages= 1052–8 |year= 1996 |pmid= 8604338 |doi=
*cite journal | author=Barbeau B, Bergeron D, Beaulieu M, "et al." |title=Characterization of the human and mouse Fli-1 promoter regions. |journal=Biochim. Biophys. Acta |volume=1307 |issue= 2 |pages= 220–32 |year= 1996 |pmid= 8679708 |doi=
*cite journal | author=Watson DK, Robinson L, Hodge DR, "et al." |title=FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements. |journal=Oncogene |volume=14 |issue= 2 |pages= 213–21 |year= 1997 |pmid= 9010223 |doi= 10.1038/sj.onc.1200839
*cite journal | author=Kwiatkowski BA, Bastian LS, Bauer TR, "et al." |title=The ets family member Tel binds to the Fli-1 oncoprotein and inhibits its transcriptional activity. |journal=J. Biol. Chem. |volume=273 |issue= 28 |pages= 17525–30 |year= 1998 |pmid= 9651344 |doi=
*cite journal | author=Carrère S, Verger A, Flourens A, "et al." |title=Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains. |journal=Oncogene |volume=16 |issue= 25 |pages= 3261–8 |year= 1998 |pmid= 9681824 |doi= 10.1038/sj.onc.1201868
*cite journal | author=Zucman-Rossi J, Legoix P, Victor JM, "et al." |title=Chromosome translocation based on illegitimate recombination in human tumors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 20 |pages= 11786–91 |year= 1998 |pmid= 9751743 |doi=
*cite journal | author=Dalgleish P, Sharrocks AD |title=The mechanism of complex formation between Fli-1 and SRF transcription factors. |journal=Nucleic Acids Res. |volume=28 |issue= 2 |pages= 560–9 |year= 2000 |pmid= 10606656 |doi=
*cite journal | author=Knoop LL, Baker SJ |title=The splicing factor U1C represses EWS/FLI-mediated transactivation. |journal=J. Biol. Chem. |volume=275 |issue= 32 |pages= 24865–71 |year= 2000 |pmid= 10827180 |doi= 10.1074/jbc.M001661200
*cite journal | author=Spyropoulos DD, Pharr PN, Lavenburg KR, "et al." |title=Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor. |journal=Mol. Cell. Biol. |volume=20 |issue= 15 |pages= 5643–52 |year= 2000 |pmid= 10891501 |doi=
*cite journal | author=Mastrangelo T, Modena P, Tornielli S, "et al." |title=A novel zinc finger gene is fused to EWS in small round cell tumor. |journal=Oncogene |volume=19 |issue= 33 |pages= 3799–804 |year= 2000 |pmid= 10949935 |doi= 10.1038/sj.onc.1203762

External links

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