TOX2

protein
Name = TOX high mobility group box family member 2
caption =


width =
HGNCid = 16095
Symbol = TOX2
AltSymbols = C20orf100, GCX-1
EntrezGene = 84969
OMIM = 611163
RefSeq = NM_001098796
UniProt = Q96NM4
PDB =
ECnumber =
Chromosome = 20
Arm = q
Band = 13.12
LocusSupplementaryData =

TOX high mobility group box family member 2, also known as TOX2, is a human gene.cite web | title = Entrez Gene: TOX high mobility group box family member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84969| accessdate = ] cite journal | author = Kajitani T, Mizutani T, Yamada K, Yazawa T, Sekiguchi T, Yoshino M, Kawata H, Miyamoto K | title = Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells | journal = Endocrinology | volume = 145 | issue = 5 | pages = 2307–18 | year = 2004 | month = May | pmid = 14764631 | doi = 10.1210/en.2003-1343 | url = | issn = ]

The protein encoded by this gene is a member of a subfamily of transcription factors that also includes TOX, TOX3, and TOX4 that share almost identical HMG-box DNA-binding domains which function to modify chromatin structure.cite journal | author = O'Flaherty E, Kaye J | title = TOX defines a conserved subfamily of HMG-box proteins | journal = BMC Genomics | volume = 4 | issue = 1 | pages = 13 | year = 2003 | month = April | pmid = 12697058 | pmc = 155677 | doi = | url = http://www.biomedcentral.com/1471-2164/4/13 | issn = ]

References