Winged-helix transcription factors

Winged-helix transcription factors

Consisting of about 110 amino acids, the domain in winged-helix transcription factors has four helices and a two-strand beta-sheet.

These proteins are classified into 17 families called FoxA-FoxQ.

Mutations in FoxP proteins are implicated in human autoimmune diseases.

ee also

* FOX proteins

External links

*


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • winged helix transcription factors — Family of transcription factors characterized by a conserved DNA binding domain found in Drosophila homeotic gene forkhead and rat hepatocyte nuclear factor 3 (HNF 3 b ). At least 80 genes with this motif are known, many with developmentally… …   Dictionary of molecular biology

  • Transcription factor — In the field of molecular biology, a transcription factor (sometimes called a sequence specific DNA binding factor) is a protein that binds to specific sequences of DNA and thereby controls the transfer (or transcription) of genetic information… …   Wikipedia

  • Microphthalmia-associated transcription factor — Identifiers Symbols MITF; MI; WS2; WS2A; bHLHe32 External IDs …   Wikipedia

  • Activating transcription factor 2 — PDB rendering based on 1bhi …   Wikipedia

  • RE1-silencing transcription factor — Identifiers Symbols REST; NRSF; XBR External IDs …   Wikipedia

  • Chicken ovalbumin upstream promoter-transcription factor — nuclear receptor subfamily 2, group F, member 1 Identifiers Symbol NR2F1 Alt. symbols ERBAL3, TFCOUP1, EAR 3, COUP TFI, TCFCOUP1, SVP44 Entrez …   Wikipedia

  • Octamer transcription factor — An octamer transcription factor is a transcription factor which binds to the ATTTGCAT sequence.[1] Examples include: Oct 1 POU2F1 Oct 2 POU2F2 Oct 3/4 – POU5F1 Oct 6 – …   Wikipedia

  • Myogenic regulatory factors — are basic helix loop helix (bHLH) transcription factors that regulate myogenesis: MyoD, Myf5, myogenin, and MRF4[1]. These proteins contain a conserved basic DNA binding domain that binds the E box DNA motif [2]. They dimerize with other HLH… …   Wikipedia

  • ETS transcription factor family — In the field of molecular biology, the ETS family is one of the largest families of transcription factors and is unique to metazoans. There are 27 genes in humans, 26 in the mouse, 10 in Caenorhabditis elegans and 9 in Drosophila. The founding… …   Wikipedia

  • Hepatocyte nuclear factors — protein Name= hepatocyte nuclear factor 1, alpha caption=Structure of the hepatocyte nuclear factor 1A (green cartoon) bound to DNA (magenta) based on the crystallographic coordinates PDB|1IC8. width= HGNCid= 11621 Symbol= TCF1 AltSymbols=… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”