KLF4

KLF4

Kruppel-like factor 4 (gut), also known as KLF4, is a human gene. [cite web | title = Entrez Gene: KLF4 Kruppel-like factor 4 (gut)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9314| accessdate = ]

PBB_Summary
section_title =
summary_text =

ee also

* Kruppel-like factors

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Rowland BD, Peeper DS |title=KLF4, p21 and context-dependent opposing forces in cancer. |journal=Nat. Rev. Cancer |volume=6 |issue= 1 |pages= 11–23 |year= 2006 |pmid= 16372018 |doi= 10.1038/nrc1780
*cite journal | author=Shields JM, Christy RJ, Yang VW |title=Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest. |journal=J. Biol. Chem. |volume=271 |issue= 33 |pages= 20009–17 |year= 1996 |pmid= 8702718 |doi=
*cite journal | author=Garrett-Sinha LA, Eberspaecher H, Seldin MF, de Crombrugghe B |title=A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells. |journal=J. Biol. Chem. |volume=271 |issue= 49 |pages= 31384–90 |year= 1997 |pmid= 8940147 |doi=
*cite journal | author=Yet SF, McA'Nulty MM, Folta SC, "et al." |title=Human EZF, a Krüppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domains. |journal=J. Biol. Chem. |volume=273 |issue= 2 |pages= 1026–31 |year= 1998 |pmid= 9422764 |doi=
*cite journal | author=Zhang W, Shields JM, Sogawa K, "et al." |title=The gut-enriched Krüppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion. |journal=J. Biol. Chem. |volume=273 |issue= 28 |pages= 17917–25 |year= 1998 |pmid= 9651398 |doi=
*cite journal | author=Foster KW, Ren S, Louro ID, "et al." |title=Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF. |journal=Cell Growth Differ. |volume=10 |issue= 6 |pages= 423–34 |year= 1999 |pmid= 10392904 |doi=
*cite journal | author=Segre JA, Bauer C, Fuchs E |title=Klf4 is a transcription factor required for establishing the barrier function of the skin. |journal=Nat. Genet. |volume=22 |issue= 4 |pages= 356–60 |year= 1999 |pmid= 10431239 |doi= 10.1038/11926
*cite journal | author=Geiman DE, Ton-That H, Johnson JM, Yang VW |title=Transactivation and growth suppression by the gut-enriched Krüppel-like factor (Krüppel-like factor 4) are dependent on acidic amino acid residues and protein-protein interaction. |journal=Nucleic Acids Res. |volume=28 |issue= 5 |pages= 1106–13 |year= 2000 |pmid= 10666450 |doi=
*cite journal | author=Zhang W, Geiman DE, Shields JM, "et al." |title=The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter. |journal=J. Biol. Chem. |volume=275 |issue= 24 |pages= 18391–8 |year= 2000 |pmid= 10749849 |doi= 10.1074/jbc.C000062200
*cite journal | author=Okano J, Opitz OG, Nakagawa H, "et al." |title=The Krüppel-like transcriptional factors Zf9 and GKLF coactivate the human keratin 4 promoter and physically interact. |journal=FEBS Lett. |volume=473 |issue= 1 |pages= 95–100 |year= 2000 |pmid= 10802067 |doi=
*cite journal | author=Higaki Y, Schullery D, Kawata Y, "et al." |title=Synergistic activation of the rat laminin gamma1 chain promoter by the gut-enriched Kruppel-like factor (GKLF/KLF4) and Sp1. |journal=Nucleic Acids Res. |volume=30 |issue= 11 |pages= 2270–9 |year= 2002 |pmid= 12034813 |doi=
*cite journal | author=Chen ZY, Shie JL, Tseng CC |title=Gut-enriched Kruppel-like factor represses ornithine decarboxylase gene expression and functions as checkpoint regulator in colonic cancer cells. |journal=J. Biol. Chem. |volume=277 |issue= 48 |pages= 46831–9 |year= 2003 |pmid= 12297499 |doi= 10.1074/jbc.M204816200
*cite journal | author=Yoon HS, Chen X, Yang VW |title=Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. |journal=J. Biol. Chem. |volume=278 |issue= 4 |pages= 2101–5 |year= 2003 |pmid= 12427745 |doi= 10.1074/jbc.M211027200
*cite journal | author=Wang N, Liu ZH, Ding F, "et al." |title=Down-regulation of gut-enriched Kruppel-like factor expression in esophageal cancer. |journal=World J. Gastroenterol. |volume=8 |issue= 6 |pages= 966–70 |year= 2003 |pmid= 12439907 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Chen X, Whitney EM, Gao SY, Yang VW |title=Transcriptional profiling of Krüppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation. |journal=J. Mol. Biol. |volume=326 |issue= 3 |pages= 665–77 |year= 2003 |pmid= 12581631 |doi=
*cite journal | author=Dang DT, Chen X, Feng J, "et al." |title=Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity. |journal=Oncogene |volume=22 |issue= 22 |pages= 3424–30 |year= 2003 |pmid= 12776194 |doi= 10.1038/sj.onc.1206413
*cite journal | author=Mao Z, Song S, Zhu Y, "et al." |title=Transcriptional regulation of A33 antigen expression by gut-enriched Krüppel-like factor. |journal=Oncogene |volume=22 |issue= 28 |pages= 4434–43 |year= 2003 |pmid= 12853980 |doi= 10.1038/sj.onc.1206508
*cite journal | author=Ohnishi S, Ohnami S, Laub F, "et al." |title=Downregulation and growth inhibitory effect of epithelial-type Krüppel-like transcription factor KLF4, but not KLF5, in bladder cancer. |journal=Biochem. Biophys. Res. Commun. |volume=308 |issue= 2 |pages= 251–6 |year= 2003 |pmid= 12901861 |doi=
*cite journal | author=Hinnebusch BF, Siddique A, Henderson JW, "et al." |title=Enterocyte differentiation marker intestinal alkaline phosphatase is a target gene of the gut-enriched Kruppel-like factor. |journal=Am. J. Physiol. Gastrointest. Liver Physiol. |volume=286 |issue= 1 |pages= G23–30 |year= 2004 |pmid= 12919939 |doi= 10.1152/ajpgi.00203.2003

External links

*
* [http://www.nextbio.com/b/home/home.nb?q=KLF4&id=34891&type=feature&name=KLF4&synonym= KLF4 microarray expression results and literature]

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • KLF4 — Factor 4 Kruppel like HUGO 6348 Símbolo KLF4 Símbolos alt. EZF; GKLF …   Wikipedia Español

  • Klf4 — Shinya Yamanaka Pour les articles homonymes, voir Shinya et Yamanaka. Shinya Yamanaka (山中 伸弥 : Yamanaka Shinya) est un medecin japonais et chercheur sur l induction des cellules souches embryonnaires et la reprogrammation des cellules… …   Wikipédia en Français

  • Kruppel-like factors — The Krüppel like family of transcription factors (Klfs), so named for their homology to the Drosophila melanogaster Krüppel protein, have been extensively studied for their roles in cell proliferation, differentiation and survival, especially in… …   Wikipedia

  • Induced pluripotent stem cell — Induced pluripotent stem cells, commonly abbreviated as iPS cells or iPSCs, are a type of pluripotent stem cell artificially derived from a non pluripotent cell, typically an adult somatic cell, by inducing a forced expression of certain genes.… …   Wikipedia

  • Индуцированные стволовые клетки — Индуцированные стволовые клетки  cтволовые клетки, полученные из каких либо иных (cоматических, репродуктивных или плюрипотентных) клеток путем эпигенетического перепрограммирования. В зависимости от степени дедифференцировки клетки при… …   Википедия

  • mir-1 microRNA precursor family — miR 1 mIR 1 microRNA precursor family Identifiers Symbol mir 1 Rfam RF00103 …   Wikipedia

  • Oct-4 — POU class 5 homeobox 1 Identifiers Symbols POU5F1; MGC22487; OCT3; OCT4; OTF 3; OTF3; OTF4; Oct 3; Oct 4 External IDs …   Wikipedia

  • Oct-4 — (аббревиатура от Octamer 4)  это транскрипционный фактор, содержащий гомеобокс, из семейства POU. Данный белок участвует в самообновлении недифференцированных эмбриональных стволовых клеток.[1] Широко используется как маркёр для… …   Википедия

  • Белки группы polycomb — (англ. Polycomb group proteins)  это семейство белков, которые способны ремоделировать хроматин. Впервые открыты у дрозофил.[1] Эти белки так видоизменяют структуру хроматина, что транскрипционные факторы не могут связываться с… …   Википедия

  • Mesenchymal-epithelial transition — A mesenchymal epithelial transition (MET) is a reversible biological process that involves the transition from motile, multipolar or spindle shaped mesenchymal cells to planar arrays of polarized cells called epithelia. MET is the reverse process …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”