OPN1MW

Opsin 1 (cone pigments), medium-wave-sensitive
Identifiers
Symbols	OPN1MW; CBBM; CBD; COD5; GCP; GOP; MGC176615; MGC177321; MGC198468; MGC198469; OPN1MW1; OPN1MW2
External IDs	OMIM: 300821 HomoloGene: 88332 GeneCards: OPN1MW Gene
Gene Ontology Molecular function • rhodopsin-like receptor activity • photoreceptor activity Cellular component • integral to plasma membrane • membrane Biological process • signal transduction • G-protein coupled receptor protein signaling pathway • visual perception • phototransduction • protein-chromophore linkage • response to stimulus Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	2652	n/a
Ensembl	n/a	n/a
UniProt	P04001	n/a
RefSeq (mRNA)	NM_000513	n/a
RefSeq (protein)	NP_000504	n/a
Location (UCSC)	n/a	n/a
PubMed search	[1]	n/a

Green-sensitive opsin is a protein that in humans is encoded by the OPN1MW gene.^[1]

See also

• Opsin

References

1. ^ "Entrez Gene: OPN1MW opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2652. 

External links

• GeneReviews/NIH/NCBI/UW entry on Red-Green Color Vision Defects

Further reading

• Applebury ML, Hargrave PA (1987). "Molecular biology of the visual pigments.". Vision Res. 26 (12): 1881–95. doi:10.1016/0042-6989(86)90115-X. PMID 3303660. 
• Winderickx J, Sanocki E, Lindsey DT, et al. (1993). "Defective colour vision associated with a missense mutation in the human green visual pigment gene.". Nat. Genet. 1 (4): 251–6. doi:10.1038/ng0792-251. PMID 1302020. 
• Neitz J, Neitz M, Jacobs GH (1990). "Analysis of fusion gene and encoded photopigment of colour-blind humans.". Nature 342 (6250): 679–82. doi:10.1038/342679a0. PMID 2574415. 
• Nathans J, Thomas D, Hogness DS (1986). "Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.". Science 232 (4747): 193–202. doi:10.1126/science.2937147. PMID 2937147. 
• Li ZY, Kljavin IJ, Milam AH (1995). "Rod photoreceptor neurite sprouting in retinitis pigmentosa.". J. Neurosci. 15 (8): 5429–38. PMID 7643192. 
• Ladekjaer-Mikkelsen AS, Rosenberg T, Jørgensen AL (1996). "A new mechanism in blue cone monochromatism.". Hum. Genet. 98 (4): 403–8. doi:10.1007/s004390050229. PMID 8792812. 
• Ferreira PA, Nakayama TA, Pak WL, Travis GH (1996). "Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.". Nature 383 (6601): 637–40. doi:10.1038/383637a0. PMID 8857542. 
• Vissers PM, Bovee-Geurts PH, Portier MD, et al. (1998). "Large-scale production and purification of the human green cone pigment: characterization of late photo-intermediates.". Biochem. J. 330 ( Pt 3): 1201–8. PMC 1219262. PMID 9494086. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1219262. 
• Bernstein SL, Wong P (1998). "Regional expression of disease-related genes in human and monkey retina.". Mol. Vis. 4: 24. PMID 9815288. 
• Hayashi T, Motulsky AG, Deeb SS (1999). "Position of a 'green-red' hybrid gene in the visual pigment array determines colour-vision phenotype.". Nat. Genet. 22 (1): 90–3. doi:10.1038/8798. PMID 10319869. 
• Ueyama H, Kuwayama S, Imai H, et al. (2002). "Novel missense mutations in red/green opsin genes in congenital color-vision deficiencies.". Biochem. Biophys. Res. Commun. 294 (2): 205–9. doi:10.1016/S0006-291X(02)00458-8. PMID 12051694. 
• Zhu X, Brown B, Li A, et al. (2003). "GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina.". J. Neurosci. 23 (14): 6152–60. PMID 12853434. 
• Bonilha VL, Hollyfield JG, Grover S, Fishman GA (2005). "Abnormal distribution of red/green cone opsins in a patient with an autosomal dominant cone dystrophy.". Ophthalmic Genet. 26 (2): 69–76. doi:10.1080/13816810590968041. PMID 16020309. 

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