GPR132

G protein-coupled receptor 132, also known as GPR132, is a human gene.cite web | title = Entrez Gene: GPR132 G protein-coupled receptor 132| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29933| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a subfamily member of the G-protein couple receptor (GPCR) superfamily. The encoded protein is a high-affinity receptor for lysophosphatidylcholine (LPC), a major phospholipid component of oxidized low density lipoprotein. This protein may react to LPC levels at sites of inflammation to limit the expansion of tissue-infiltrating cells. A similar protein in mouse is involved in cell cycle progression.cite web | title = Entrez Gene: GPR132 G protein-coupled receptor 132| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29933| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Weng Z, Fluckiger AC, Nisitani S, "et al." |title=A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 21 |pages= 12334–9 |year= 1998 |pmid= 9770487 |doi=
*cite journal | author=Kabarowski JH, Zhu K, Le LQ, "et al." |title=Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A. |journal=Science |volume=293 |issue= 5530 |pages= 702–5 |year= 2001 |pmid= 11474113 |doi= 10.1126/science.1061781
*cite journal | author=Le LQ, Kabarowski JH, Wong S, "et al." |title=Positron emission tomography imaging analysis of G2A as a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene. |journal=Cancer Cell |volume=1 |issue= 4 |pages= 381–91 |year= 2002 |pmid= 12086852 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Rikitake Y, Hirata K, Yamashita T, "et al." |title=Expression of G2A, a receptor for lysophosphatidylcholine, by macrophages in murine, rabbit, and human atherosclerotic plaques. |journal=Arterioscler. Thromb. Vasc. Biol. |volume=22 |issue= 12 |pages= 2049–53 |year= 2002 |pmid= 12482833 |doi=
*cite journal | author=Lin P, Ye RD |title=The lysophospholipid receptor G2A activates a specific combination of G proteins and promotes apoptosis. |journal=J. Biol. Chem. |volume=278 |issue= 16 |pages= 14379–86 |year= 2003 |pmid= 12586833 |doi= 10.1074/jbc.M209101200
*cite journal | author=Lum H, Qiao J, Walter RJ, "et al." |title=Inflammatory stress increases receptor for lysophosphatidylcholine in human microvascular endothelial cells. |journal=Am. J. Physiol. Heart Circ. Physiol. |volume=285 |issue= 4 |pages= H1786–9 |year= 2003 |pmid= 12805023 |doi= 10.1152/ajpheart.00359.2003
*cite journal | author=Murakami N, Yokomizo T, Okuno T, Shimizu T |title=G2A is a proton-sensing G-protein-coupled receptor antagonized by lysophosphatidylcholine. |journal=J. Biol. Chem. |volume=279 |issue= 41 |pages= 42484–91 |year= 2004 |pmid= 15280385 |doi= 10.1074/jbc.M406561200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Witte ON, Kabarowski JH, Xu Y, "et al." |title=Retraction. |journal=Science |volume=307 |issue= 5707 |pages= 206 |year= 2005 |pmid= 15653487 |doi= 10.1126/science.307.5707.206b
*cite journal | author=Radu CG, Nijagal A, McLaughlin J, "et al." |title=Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 5 |pages= 1632–7 |year= 2005 |pmid= 15665078 |doi= 10.1073/pnas.0409415102
*cite journal | author=Obinata H, Hattori T, Nakane S, "et al." |title=Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A. |journal=J. Biol. Chem. |volume=280 |issue= 49 |pages= 40676–83 |year= 2006 |pmid= 16236715 |doi= 10.1074/jbc.M507787200
*cite journal | author=Frasch SC, Zemski-Berry K, Murphy RC, "et al." |title=Lysophospholipids of different classes mobilize neutrophil secretory vesicles and induce redundant signaling through G2A. |journal=J. Immunol. |volume=178 |issue= 10 |pages= 6540–8 |year= 2007 |pmid= 17475884 |doi=

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes