FZD6

Frizzled homolog 6 (Drosophila), also known as FZD6, is a human gene.cite web | title = Entrez Gene: FZD6 frizzled homolog 6 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8323| accessdate = ]

PBB_Summary
section_title =
summary_text = Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD6 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and 7 transmembrane domains. However, unlike many other Fz family members, FDZ6 does not contain a C-terminal PDZ domain-binding motif.cite web | title = Entrez Gene: FZD6 frizzled homolog 6 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8323| accessdate = ]

ee also

* Frizzled

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wang Y, Macke JP, Abella BS, "et al." |title=A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. |journal=J. Biol. Chem. |volume=271 |issue= 8 |pages= 4468–76 |year= 1996 |pmid= 8626800 |doi=
*cite journal | author=Finch PW, He X, Kelley MJ, "et al." |title=Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 13 |pages= 6770–5 |year= 1997 |pmid= 9192640 |doi=
*cite journal | author=Tokuhara M, Hirai M, Atomi Y, "et al." |title=Molecular cloning of human Frizzled-6. |journal=Biochem. Biophys. Res. Commun. |volume=243 |issue= 2 |pages= 622–7 |year= 1998 |pmid= 9480858 |doi= 10.1006/bbrc.1998.8143
*cite journal | author=Bafico A, Gazit A, Pramila T, "et al." |title=Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling. |journal=J. Biol. Chem. |volume=274 |issue= 23 |pages= 16180–7 |year= 1999 |pmid= 10347172 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Golan T, Yaniv A, Bafico A, "et al." |title=The human Frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt. beta-catenin signaling cascade. |journal=J. Biol. Chem. |volume=279 |issue= 15 |pages= 14879–88 |year= 2004 |pmid= 14747478 |doi= 10.1074/jbc.M306421200
*cite journal | author=Omoto S, Hayashi T, Kitahara K, "et al." |title=Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R). |journal=Ophthalmic Genet. |volume=25 |issue= 2 |pages= 81–90 |year= 2004 |pmid= 15370539 |doi= 10.1080/13816810490514270
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Sirchia R, Luparello C |title=Mid-region parathyroid hormone-related protein (PTHrP) and gene expression of MDA-MB231 breast cancer cells. |journal=Biol. Chem. |volume=388 |issue= 5 |pages= 457–65 |year= 2007 |pmid= 17516841 |doi= 10.1515/BC.2007.059

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