Glucagon receptor family

Glucagon receptor family

The glucagon receptor familycite journal | author = Brubaker PL, Drucker DJ | title = Structure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors | journal = Recept. Channels | volume = 8 | issue = 3-4 | pages = 179–88 | year = 2002 | pmid = 12529935| url = http://www.glucagon.com/pdfs/Receptors%20and%20Channels.pdf | accessdate = 2008-07-14 | doi = 10.1080/10606820213687 ] is a group of closely related G-protein coupled receptors which include:

* Glucagon receptor
* Glucagon-like peptide 1 receptor
* Glucagon-like peptide 2 receptor
* Gastric inhibitory polypeptide receptor

The first three receptors bind closely related peptide hormones (glucagon, glucagon-like peptide-1, glucagon-like peptide-2) derived from the proglucagon polypeptide. The last receptor binds gastric inhibitory polypeptide.

References

External links

* [http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1286 IUPHAR GPCR Database - Glucagon receptor family]


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