GPRC6A

GPRC6A

G protein-coupled receptor, family C, group 6, member A, also known as GPRC6A, is a human gene.cite web | title = Entrez Gene: GPRC6A G protein-coupled receptor, family C, group 6, member A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=222545| accessdate = ] This receptor functions as a sensor of L-amino acids.cite journal | author = Wellendorph P, Hansen KB, Balsgaard A, Greenwood JR, Egebjerg J, Bräuner-Osborne H | title = Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids | journal = Mol. Pharmacol. | volume = 67 | issue = 3 | pages = 589–97 | year = 2005 | pmid = 15576628 | doi = 10.1124/mol.104.007559 | issn = ]

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References

Further reading

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*cite journal | author=Harrington JJ, Sherf B, Rundlett S, "et al." |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440–5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107
*cite journal | author=Takeda S, Kadowaki S, Haga T, "et al." |title=Identification of G protein-coupled receptor genes from the human genome sequence. |journal=FEBS Lett. |volume=520 |issue= 1-3 |pages= 97–101 |year= 2002 |pmid= 12044878 |doi=
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Wellendorph P, Bräuner-Osborne H |title=Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor. |journal=Gene |volume=335 |issue= |pages= 37–46 |year= 2004 |pmid= 15194188 |doi= 10.1016/j.gene.2004.03.003
*cite journal | author=Wellendorph P, Hansen KB, Balsgaard A, "et al." |title=Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids. |journal=Mol. Pharmacol. |volume=67 |issue= 3 |pages= 589–97 |year= 2005 |pmid= 15576628 |doi= 10.1124/mol.104.007559
*cite journal | author=Pi M, Faber P, Ekema G, "et al." |title=Identification of a novel extracellular cation-sensing G-protein-coupled receptor. |journal=J. Biol. Chem. |volume=280 |issue= 48 |pages= 40201–9 |year= 2006 |pmid= 16199532 |doi= 10.1074/jbc.M505186200

External links

* [http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2968 IUPHAR GPCR Database - GPRC6]
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