Vasoactive intestinal peptide receptor
- Vasoactive intestinal peptide receptor
protein
Name = vasoactive intestinal peptide receptor 1
caption =
width =
HGNCid = 12694
Symbol = VIPR1
AltSymbols = RDC1, HVR1, VAPC1
EntrezGene = 7433
OMIM = 192321
RefSeq = NM_004624
UniProt = P32241
PDB =
ECnumber =
Chromosome = 3
Arm = p
Band = 22
LocusSupplementaryData = protein
Name = vasoactive intestinal peptide receptor 2
caption =
width =
HGNCid = 12695
Symbol = VIPR2
AltSymbols = VPAC2
EntrezGene = 7434
OMIM = 601970
RefSeq = NM_003382
UniProt = P41587
PDB =
ECnumber =
Chromosome = 7
Arm = q
Band = 36.3
LocusSupplementaryData = protein
Name = adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
caption =
width =
HGNCid = 242
Symbol = ADCYAP1R1
AltSymbols = PACAPR
EntrezGene = 117
OMIM = 102981
RefSeq = NM_001118
UniProt = P41586
PDB =
ECnumber =
Chromosome = 7
Arm = p
Band = 14
LocusSupplementaryData = There are two known receptors for the vasoactive intestinal peptide (VIP) termed VPAC1 and VPAC2.[cite journal | author = Laburthe M, Couvineau A, Marie JC | title = VPAC receptors for VIP and PACAP | journal = Recept. Channels | volume = 8 | issue = 3-4 | pages = 137–53 | year = 2002 | pmid = 12529932 | doi = | issn = ] ][cite journal | author = Laburthe M, Couvineau A | title = Molecular pharmacology and structure of VPAC Receptors for VIP and PACAP | journal = Regul. Pept. | volume = 108 | issue = 2-3 | pages = 165–73 | year = 2002 | pmid = 12220741 | doi = | issn = ] These receptors bind both VIP and pituitary adenylate cyclase-activating polypeptide to some degree. Both receptors are members of the 7 transmembrane g protein-coupled family of receptors.]VPAC1 is distributed widely in the CNS, liver, lung, intestine and T-lymphocytes.
VPAC2 is found in the CNS, pancreas, skeletal muscle, heart, kidney, adipose tissue, testis, and stomach.
References
External links
* [http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1300 IUPHAR GPCR Database - VIP and PACAP Receptors]
*
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