Free fatty acid receptor 1

Free fatty acid receptor 1, also known as FFAR1, is a human gene.cite web | title = Entrez Gene: FFAR1 free fatty acid receptor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2864| accessdate = ]

PBB_Summary
section_title =
summary_text =

ee also

* Free fatty acid receptor

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Brown AJ, Jupe S, Briscoe CP |title=A family of fatty acid binding receptors. |journal=DNA Cell Biol. |volume=24 |issue= 1 |pages= 54–61 |year= 2005 |pmid= 15684720 |doi= 10.1089/dna.2005.24.54
*cite journal | author=Sawzdargo M, George SR, Nguyen T, "et al." |title=A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1. |journal=Biochem. Biophys. Res. Commun. |volume=239 |issue= 2 |pages= 543–7 |year= 1997 |pmid= 9344866 |doi= 10.1006/bbrc.1997.7513
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Briscoe CP, Tadayyon M, Andrews JL, "et al." |title=The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. |journal=J. Biol. Chem. |volume=278 |issue= 13 |pages= 11303–11 |year= 2003 |pmid= 12496284 |doi= 10.1074/jbc.M211495200
*cite journal | author=Kotarsky K, Nilsson NE, Flodgren E, "et al." |title=A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs. |journal=Biochem. Biophys. Res. Commun. |volume=301 |issue= 2 |pages= 406–10 |year= 2003 |pmid= 12565875 |doi=
*cite journal | author=Itoh Y, Kawamata Y, Harada M, "et al." |title=Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. |journal=Nature |volume=422 |issue= 6928 |pages= 173–6 |year= 2003 |pmid= 12629551 |doi= 10.1038/nature01478
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hardy S, St-Onge GG, Joly E, "et al." |title=Oleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40. |journal=J. Biol. Chem. |volume=280 |issue= 14 |pages= 13285–91 |year= 2005 |pmid= 15695516 |doi= 10.1074/jbc.M410922200
*cite journal | author=Ogawa T, Hirose H, Miyashita K, "et al." |title=GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men. |journal=Metab. Clin. Exp. |volume=54 |issue= 3 |pages= 296–9 |year= 2005 |pmid= 15736105 |doi= 10.1016/j.metabol.2004.09.008
*cite journal | author=Tomita T, Masuzaki H, Noguchi M, "et al." |title=GPR40 gene expression in human pancreas and insulinoma. |journal=Biochem. Biophys. Res. Commun. |volume=338 |issue= 4 |pages= 1788–90 |year= 2006 |pmid= 16289108 |doi= 10.1016/j.bbrc.2005.10.161
*cite journal | author=Tomita T, Masuzaki H, Iwakura H, "et al." |title=Expression of the gene for a membrane-bound fatty acid receptor in the pancreas and islet cell tumours in humans: evidence for GPR40 expression in pancreatic beta cells and implications for insulin secretion. |journal=Diabetologia |volume=49 |issue= 5 |pages= 962–8 |year= 2006 |pmid= 16525841 |doi= 10.1007/s00125-006-0193-8
*cite journal | author=Stoddart LA, Brown AJ, Milligan G |title=Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3- [35S] thio)triphosphate binding studies reflects binding of an endogenous agonist. |journal=Mol. Pharmacol. |volume=71 |issue= 4 |pages= 994–1005 |year= 2007 |pmid= 17200419 |doi= 10.1124/mol.106.031534
*cite journal | author=Bartoov-Shifman R, Ridner G, Bahar K, "et al." |title=Regulation of the gene encoding GPR40, a fatty acid receptor expressed selectively in pancreatic beta cells. |journal=J. Biol. Chem. |volume=282 |issue= 32 |pages= 23561–71 |year= 2007 |pmid= 17525159 |doi= 10.1074/jbc.M702115200
*cite journal | author=Sum CS, Tikhonova IG, Neumann S, "et al." |title=Identification of residues important for agonist recognition and activation in GPR40. |journal=J. Biol. Chem. |volume=282 |issue= 40 |pages= 29248–55 |year= 2007 |pmid= 17699519 |doi= 10.1074/jbc.M705077200

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes