Lysophosphatidic acid receptor 4
Symbols LPAR4; GPR23; LPA4; P2RY9; P2Y5-LIKE; P2Y9
External IDs OMIM300086 MGI1925384 HomoloGene3871 IUPHAR: GeneCards: LPAR4 Gene
RNA expression pattern
PBB GE GPR23 206960 at tn.png
More reference expression data
Species Human Mouse
Entrez 2846 78134
Ensembl ENSG00000147145 ENSMUSG00000049929
UniProt Q99677 Q80UD5
RefSeq (mRNA) NM_005296 NM_175271.4
RefSeq (protein) NP_005287 NP_780480.2
Location (UCSC) Chr X:
78 – 78.01 Mb
Chr X:
104.12 – 104.13 Mb
PubMed search [1] [2]

Lysophosphatidic acid receptor 4 also known as LPA4 is a protein that in humans is encoded by the LPAR4 gene.[1][2][3] LPA4 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).[4]

See also


  1. ^ "Entrez Gene: GPR23 G protein-coupled receptor 23". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2846. 
  2. ^ Janssens R, Boeynaems JM, Godart M, Communi D (July 1997). "Cloning of a human heptahelical receptor closely related to the P2Y5 receptor". Biochem. Biophys. Res. Commun. 236 (1): 106–12. doi:10.1006/bbrc.1997.6895. PMID 9223435. 
  3. ^ O'Dowd BF, Nguyen T, Jung BP, Marchese A, Cheng R, Heng HH, Kolakowski LF, Lynch KR, George SR (March 1997). "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes". Gene 187 (1): 75–81. doi:10.1016/S0378-1119(96)00722-6. PMID 9073069. 
  4. ^ Choi JW, Herr DR, Noguchi K, Yung YC, Lee C-W, Mutoh T, Lin M-E, Teo ST, Park KE, Mosley AN, Chun J (January 2010). "LPA Receptors: Subtypes and Biological Actions". Annual Review of Pharmacology and Toxicology 50 (1): 157–186. doi:10.1146/annurev.pharmtox.010909.105753. PMID 20055701. http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.pharmtox.010909.105753. 

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.