GPR44

G protein-coupled receptor 44, also known as GPR44, is a human gene.cite web | title = Entrez Gene: GPR44 G protein-coupled receptor 44| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11251| accessdate = ] GPR44 has also been designated as CD294 (cluster of differentiation 294).

PBB_Summary
section_title =
summary_text = G protein-coupled receptors (GPCRs), such as GPR44, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response. [supplied by OMIM] cite web | title = Entrez Gene: GPR44 G protein-coupled receptor 44| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11251| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Nagata K |title=CRTH2. |journal=J. Biol. Regul. Homeost. Agents |volume=17 |issue= 4 |pages= 334–7 |year= 2004 |pmid= 15065763 |doi=
*cite journal | author=Chiba T, Kanda A, Ueki S, "et al." |title=Possible novel receptor for PGD2 on human bronchial epithelial cells. |journal=Int. Arch. Allergy Immunol. |volume=143 Suppl 1 |issue= |pages= 23–7 |year= 2007 |pmid= 17541272 |doi= 10.1159/000101400
*cite journal | author=Nagata K, Tanaka K, Ogawa K, "et al." |title=Selective expression of a novel surface molecule by human Th2 cells in vivo. |journal=J. Immunol. |volume=162 |issue= 3 |pages= 1278–86 |year= 1999 |pmid= 9973380 |doi=
*cite journal | author=Marchese A, Sawzdargo M, Nguyen T, "et al." |title=Discovery of three novel orphan G-protein-coupled receptors. |journal=Genomics |volume=56 |issue= 1 |pages= 12–21 |year= 1999 |pmid= 10036181 |doi= 10.1006/geno.1998.5655
*cite journal | author=Hirai H, Tanaka K, Yoshie O, "et al." |title=Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2. |journal=J. Exp. Med. |volume=193 |issue= 2 |pages= 255–61 |year= 2001 |pmid= 11208866 |doi=
*cite journal | author=Hirai H, Tanaka K, Takano S, "et al." |title=Cutting edge: agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2. |journal=J. Immunol. |volume=168 |issue= 3 |pages= 981–5 |year= 2002 |pmid= 11801628 |doi=
*cite journal | author=Iwasaki M, Nagata K, Takano S, "et al." |title=Association of a new-type prostaglandin D2 receptor CRTH2 with circulating T helper 2 cells in patients with atopic dermatitis. |journal=J. Invest. Dermatol. |volume=119 |issue= 3 |pages= 609–16 |year= 2002 |pmid= 12230502 |doi= 10.1046/j.1523-1747.2002.01862.x
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Böhm E, Sturm GJ, Weiglhofer I, "et al." |title=11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. |journal=J. Biol. Chem. |volume=279 |issue= 9 |pages= 7663–70 |year= 2004 |pmid= 14668348 |doi= 10.1074/jbc.M310270200
*cite journal | author=Huang JL, Gao PS, Mathias RA, "et al." |title=Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability. |journal=Hum. Mol. Genet. |volume=13 |issue= 21 |pages= 2691–7 |year= 2005 |pmid= 15345705 |doi= 10.1093/hmg/ddh279
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Venet F, Lepape A, Debard AL, "et al." |title=The Th2 response as monitored by CRTH2 or CCR3 expression is severely decreased during septic shock. |journal=Clin. Immunol. |volume=113 |issue= 3 |pages= 278–84 |year= 2004 |pmid= 15507393 |doi= 10.1016/j.clim.2004.07.005
*cite journal | author=Gazi L, Gyles S, Rose J, "et al." |title=Delta12-prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes. |journal=Prostaglandins Other Lipid Mediat. |volume=75 |issue= 1-4 |pages= 153–67 |year= 2005 |pmid= 15789622 |doi=
*cite journal | author=Hata AN, Lybrand TP, Breyer RM |title=Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2. |journal=J. Biol. Chem. |volume=280 |issue= 37 |pages= 32442–51 |year= 2005 |pmid= 16030019 |doi= 10.1074/jbc.M502563200
*cite journal | author=Sandig H, Andrew D, Barnes AA, "et al." |title=9alpha,11beta-PGF2 and its stereoisomer PGF2alpha are novel agonists of the chemoattractant receptor, CRTH2. |journal=FEBS Lett. |volume=580 |issue= 2 |pages= 373–9 |year= 2006 |pmid= 16378605 |doi= 10.1016/j.febslet.2005.11.052
*cite journal | author=Schratl P, Royer JF, Kostenis E, "et al." |title=The role of the prostaglandin D2 receptor, DP, in eosinophil trafficking. |journal=J. Immunol. |volume=179 |issue= 7 |pages= 4792–9 |year= 2007 |pmid= 17878378 |doi=

External links

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