- TAS1R1
Taste receptor, type 1, member 1, also known as TAS1R1, is a human
gene .cite web | title = Entrez Gene: TAS1R1 taste receptor, type 1, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80835| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding several different isoforms have been found for this gene.cite web | title = Entrez Gene: TAS1R1 taste receptor, type 1, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80835| accessdate = ]ee also
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Taste receptor References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS |title=The receptors and cells for mammalian taste. |journal=Nature |volume=444 |issue= 7117 |pages= 288–94 |year= 2007 |pmid= 17108952 |doi= 10.1038/nature05401
*cite journal | author=Hoon MA, Adler E, Lindemeier J, "et al." |title=Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity. |journal=Cell |volume=96 |issue= 4 |pages= 541–51 |year= 1999 |pmid= 10052456 |doi=
*cite journal | author=Makalowska I, Sood R, Faruque MU, "et al." |title=Identification of six novel genes by experimental validation of GeneMachine predicted genes. |journal=Gene |volume=284 |issue= 1-2 |pages= 203–13 |year= 2002 |pmid= 11891061 |doi=
*cite journal | author=Nelson G, Chandrashekar J, Hoon MA, "et al." |title=An amino-acid taste receptor. |journal=Nature |volume=416 |issue= 6877 |pages= 199–202 |year= 2002 |pmid= 11894099 |doi= 10.1038/nature726
*cite journal | author=Li X, Staszewski L, Xu H, "et al." |title=Human receptors for sweet and umami taste. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 7 |pages= 4692–6 |year= 2002 |pmid= 11917125 |doi= 10.1073/pnas.072090199
*cite journal | author=Liao J, Schultz PG |title=Three sweet receptor genes are clustered in human chromosome 1. |journal=Mamm. Genome |volume=14 |issue= 5 |pages= 291–301 |year= 2003 |pmid= 12856281 |doi= 10.1007/s00335-002-2233-0
*cite journal | author=Xu H, Staszewski L, Tang H, "et al." |title=Different functional roles of T1R subunits in the heteromeric taste receptors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 39 |pages= 14258–63 |year= 2005 |pmid= 15353592 |doi= 10.1073/pnas.0404384101
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Sainz E, Cavenagh MM, LopezJimenez ND, "et al." |title=The G-protein coupling properties of the human sweet and amino acid taste receptors. |journal=Dev Neurobiol |volume=67 |issue= 7 |pages= 948–59 |year= 2007 |pmid= 17506496 |doi= 10.1002/dneu.20403PBB_Controls
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