MAS1

MAS1

MAS1 oncogene, also known as MAS1, is a human gene.cite web | title = Entrez Gene: MAS1 MAS1 oncogene| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4142| accessdate = ]

PBB_Summary
section_title =
summary_text = The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.cite web | title = Entrez Gene: MAS1 MAS1 oncogene| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4142| accessdate = ]

ee also

* MAS1 oncogene

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hanley MR |title=Molecular and cell biology of angiotensin receptors. |journal=J. Cardiovasc. Pharmacol. |volume=18 Suppl 2 |issue= |pages= S7–13 |year= 1992 |pmid= 1725048 |doi=
*cite journal | author=Hanley MR, Cheung WT, Hawkins P, "et al." |title=The mas oncogene as a neural peptide receptor: expression, regulation and mechanism of action. |journal=Ciba Found. Symp. |volume=150 |issue= |pages= 23–38; discussion 38–46 |year= 1990 |pmid= 2197067 |doi=
*cite journal | author=Rabin M, Birnbaum D, Young D, "et al." |title=Human ros1 and mas1 oncogenes located in regions of chromosome 6 associated with tumor-specific rearrangements. |journal=Oncogene Res. |volume=1 |issue= 2 |pages= 169–78 |year= 1988 |pmid= 3329713 |doi=
*cite journal | author=Jackson TR, Blair LA, Marshall J, "et al." |title=The mas oncogene encodes an angiotensin receptor. |journal=Nature |volume=335 |issue= 6189 |pages= 437–40 |year= 1988 |pmid= 3419518 |doi= 10.1038/335437a0
*cite journal | author=Young D, Waitches G, Birchmeier C, "et al." |title=Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains. |journal=Cell |volume=45 |issue= 5 |pages= 711–9 |year= 1986 |pmid= 3708691 |doi=
*cite journal | author=Riesewijk AM, Schepens MT, Mariman EM, "et al." |title=The MAS proto-oncogene is not imprinted in humans. |journal=Genomics |volume=35 |issue= 2 |pages= 380–2 |year= 1996 |pmid= 8661154 |doi= 10.1006/geno.1996.0372
*cite journal | author=Xu X, Quiambao AB, Roveri L, "et al." |title=Degeneration of cone photoreceptors induced by expression of the Mas1 protooncogene. |journal=Exp. Neurol. |volume=163 |issue= 1 |pages= 207–19 |year= 2000 |pmid= 10785460 |doi= 10.1006/exnr.2000.7370
*cite journal | author=Alenina N, Baranova T, Smirnow E, "et al." |title=Cell type-specific expression of the Mas proto-oncogene in testis. |journal=J. Histochem. Cytochem. |volume=50 |issue= 5 |pages= 691–6 |year= 2002 |pmid= 11967280 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Santos RA, Simoes e Silva AC, Maric C, "et al." |title=Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 14 |pages= 8258–63 |year= 2003 |pmid= 12829792 |doi= 10.1073/pnas.1432869100
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Canals M, Jenkins L, Kellett E, Milligan G |title=Up-regulation of the angiotensin II type 1 receptor by the MAS proto-oncogene is due to constitutive activation of Gq/G11 by MAS. |journal=J. Biol. Chem. |volume=281 |issue= 24 |pages= 16757–67 |year= 2006 |pmid= 16611642 |doi= 10.1074/jbc.M601121200

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