MAS1 oncogene

MAS1 oncogene

protein
Name = MAS1 oncogene
caption =


width =
HGNCid = 6899
Symbol = MAS1
AltSymbols =
EntrezGene = 4142
OMIM = 165180
RefSeq = NM_002377
UniProt = P04201
PDB =
ECnumber =
Chromosome = 6
Arm = q
Band = 24
LocusSupplementaryData = -q27protein
Name = MAS1 oncogene-like
caption =


width =
HGNCid = 13961
Symbol = MAS1L
AltSymbols =
EntrezGene = 116511
OMIM = 607235
RefSeq = NM_052967
UniProt = P35410
PDB =
ECnumber =
Chromosome = 6
Arm = p
Band = 21
LocusSupplementaryData =

The MAS1 oncogene is a G protein-coupled receptorcite journal | author = Young D, Waitches G, Birchmeier C, Fasano O, Wigler M | title = Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains | journal = Cell | volume = 45 | issue = 5 | pages = 711–9 | year = 1986 | pmid = 3708691 | doi = 10.1016/0092-8674(86)90785-3 | issn = ] which binds the angiotensin-II metabolite angiotensin-(1-7).cite journal | author = Santos RA, Simoes e Silva AC, Maric C, Silva DM, Machado RP, de Buhr I, Heringer-Walther S, Pinheiro SV, Lopes MT, Bader M, Mendes EP, Lemos VS, Campagnole-Santos MJ, Schultheiss HP, Speth R, Walther T | title = Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 100 | issue = 14 | pages = 8258–63 | year = 2003 | pmid = 12829792 | doi = 10.1073/pnas.1432869100 | issn = ] cite journal | author = Santos RA, Ferreira AJ | title = Angiotensin-(1-7) and the renin-angiotensin system | journal = Curr. Opin. Nephrol. Hypertens. | volume = 16 | issue = 2 | pages = 122–8 | year = 2007 | pmid = 17293687 | doi = 10.1097/MNH.0b013e328031f362 | issn = ] The MAS1 receptor when activated by binding angiotensin-(1-7) opposes many of the effects of angiotensin-II activated angiotensin receptor. Hence MAS1 receptor agonists have similar therapeutic effects as angiotensin-II receptor antagonists including lowering blood pressure.cite journal | author = Santos RA, Ferreira AJ | title = Pharmacological effects of AVE 0991, a nonpeptide angiotensin-(1-7) receptor agonist | journal = Cardiovascular drug reviews | volume = 24 | issue = 3-4 | pages = 239–46 | year = 2006 | pmid = 17214600 | doi = 10.1111/j.1527-3466.2006.00239.x | issn = ]

References

External links

* [http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=3181 IUPHAR GPCR Database - MAS1]
* [http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=3182 IUPHAR GPCR Database - MAS1L]
*


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  • MAS1 — oncogene, also known as MAS1, is a human gene.cite web | title = Entrez Gene: MAS1 MAS1 oncogene| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=4142| accessdate = ] PBB Summary section title = summary text …   Wikipedia

  • MAS1L — MAS1 oncogene like, also known as MAS1L, is a human gene.cite web | title = Entrez Gene: MAS1L MAS1 oncogene like| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=116511| accessdate = ] PBB Summary section… …   Wikipedia

  • Rhodopsin-like receptors — Pfam box Symbol = 7tm 1 Name = Rhodopsin like receptors width = caption = Pfam= PF00001 InterPro= IPR000276 SMART= PROSITE = PDOC00211 SCOP = 1f88 TCDB = OPM family= 6 OPM protein= 1gzm PDB=Rhodopsin like receptors are the largest group of G… …   Wikipedia

  • MRGPRD — MAS related GPR, member D, also known as MRGPRD, is a human gene.cite web | title = Entrez Gene: MRGPRD MAS related GPR, member D| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=116512| accessdate = ] PBB… …   Wikipedia

  • MRGPRE — MAS related GPR, member E, also known as MRGPRE, is a human gene.cite web | title = Entrez Gene: MRGPRE MAS related GPR, member E| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=116534| accessdate = ] PBB… …   Wikipedia

  • MRGPRX2 — MAS related GPR, member X2, also known as MRGPRX2, is a human gene.cite web | title = Entrez Gene: MRGPRX2 MAS related GPR, member X2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=117194| accessdate = ]… …   Wikipedia

  • MRGPRX3 — MAS related GPR, member X3, also known as MRGPRX3, is a human gene.cite web | title = Entrez Gene: MRGPRX3 MAS related GPR, member X3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=117195| accessdate = ]… …   Wikipedia

  • MRGPRX4 — MAS related GPR, member X4, also known as MRGPRX4, is a human gene.cite web | title = Entrez Gene: MRGPRX4 MAS related GPR, member X4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=117196| accessdate = ]… …   Wikipedia

  • MRGPRF — MAS related GPR, member F, also known as MRGPRF, is a human gene.cite web | title = Entrez Gene: MRGPRF MAS related GPR, member F| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=219928| accessdate = ] PBB… …   Wikipedia

  • MRGPRX1 — MAS related GPR, member X1, also known as MRGPRX1, is a human gene.cite web | title = Entrez Gene: MRGPRX1 MAS related GPR, member X1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=259249| accessdate = ]… …   Wikipedia

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