- 5-HT1E receptor
5-hydroxytryptamine (serotonin) receptor 1E, also known as HTR1E, is a
5-HT1 receptor , but also denotes the humangene encoding it.cite web | title = Entrez Gene: HTR1E 5-hydroxytryptamine (serotonin) receptor 1E| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3354| accessdate = ]PBB_Summary
section_title =
summary_text =Ligands
No highly selective 5HT1E ligands are available so far.
Agonists
*BRL-54443 (5-Hydroxy-3-(1-methylpiperidin-4-yl)-1H-indole) - mixed 5HT1E/1F agonist
Antagonists
None as yet.
ee also
* 5-HT1 receptor
*5-HT receptor References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Zgombick JM, Schechter LE, Macchi M, "et al." |title=Human gene S31 encodes the pharmacologically defined serotonin 5-hydroxytryptamine1E receptor. |journal=Mol. Pharmacol. |volume=42 |issue= 2 |pages= 180–5 |year= 1992 |pmid= 1513320 |doi=
*cite journal | author=McAllister G, Charlesworth A, Snodin C, "et al." |title=Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 12 |pages= 5517–21 |year= 1992 |pmid= 1608964 |doi=
*cite journal | author=Levy FO, Gudermann T, Birnbaumer M, "et al." |title=Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase. |journal=FEBS Lett. |volume=296 |issue= 2 |pages= 201–6 |year= 1992 |pmid= 1733778 |doi=
*cite journal | author=Levy FO, Holtgreve-Grez H, Taskén K, "et al." |title=Assignment of the gene encoding the 5-HT1E serotonin receptor (S31) (locus HTR1E) to human chromosome 6q14-q15. |journal=Genomics |volume=22 |issue= 3 |pages= 637–40 |year= 1995 |pmid= 8001977 |doi= 10.1006/geno.1994.1439
*cite journal | author=Pierce PA, Xie GX, Meuser T, Peroutka SJ |title=5-Hydroxytryptamine receptor subtype messenger RNAs in human dorsal root ganglia: a polymerase chain reaction study. |journal=Neuroscience |volume=81 |issue= 3 |pages= 813–9 |year= 1997 |pmid= 9316030 |doi=
*cite journal | author=Cargill M, Altshuler D, Ireland J, "et al." |title=Characterization of single-nucleotide polymorphisms in coding regions of human genes. |journal=Nat. Genet. |volume=22 |issue= 3 |pages= 231–8 |year= 1999 |pmid= 10391209 |doi= 10.1038/10290
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134PBB_Controls
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