Galanin receptor

protein
Name = galanin receptor 1
caption =


width =
HGNCid = 4132
Symbol = GALR1
AltSymbols = GALNR1, GALNR
EntrezGene = 2587
OMIM = 600377
RefSeq = NM_001480
UniProt = P47211
PDB =
ECnumber =
Chromosome = 18
Arm = q
Band = 23
LocusSupplementaryData = protein
Name = galanin receptor 2
caption =


width =
HGNCid = 4133
Symbol = GALR2
AltSymbols =
EntrezGene = 8811
OMIM = 603691
RefSeq = NM_003857
UniProt = O43603
PDB =
ECnumber =
Chromosome = 17
Arm = q
Band = 25.3
LocusSupplementaryData = protein
Name = galanin receptor 3
caption =


width =
HGNCid = 4134
Symbol = GALR3
AltSymbols =
EntrezGene = 8484
OMIM = 603692
RefSeq = NM_003614
UniProt = O60755
PDB =
ECnumber =
Chromosome = 22
Arm = q
Band = 12.2
LocusSupplementaryData = -13.1The galanin receptor is a G protein-coupled receptor, or metabotropic receptor which binds galanin.cite journal | author = Lang R, Gundlach AL, Kofler B | title = The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease | journal = Pharmacol. Ther. | volume = 115 | issue = 2 | pages = 177–207 | year = 2007 | pmid = 17604107 | doi = 10.1016/j.pharmthera.2007.05.009 | issn = ]

So far three subtypes are known to exist: GAL-R1, GAL-R2, and GAL-R3.cite journal | author = Branchek TA, Smith KE, Gerald C, Walker MW | title = Galanin receptor subtypes | journal = Trends Pharmacol. Sci. | volume = 21 | issue = 3 | pages = 109–17 | year = 2000 | pmid = 10689365 | doi = | issn = ] The specific function of each subtype remains to be fully elucidated, although great progress is currently being made in this respect with the generation of receptor subtype-specific knockout mice.

Galanin receptors can be found throughout the peripheral and central nervous systems and the endocrine system.

References

External links

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* [http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1333 IUPHAR GPCR Database - Galanin Receptors]