TAS2R38

TAS2R38 is a bitter taste receptorcite journal | author = Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ | title = Identification and characterization of human taste receptor genes belonging to the TAS2R family | journal = Cytogenet. Genome Res. | volume = 98 | issue = 1 | pages = 45–53 | year = 2002 | pmid = 12584440 | doi = 10.1159/000068546 | issn = ] cite journal | author = Drayna D, Coon H, Kim UK, Elsner T, Cromer K, Otterud B, Baird L, Peiffer AP, Leppert M | title = Genetic analysis of a complex trait in the Utah Genetic Reference Project: a major locus for PTC taste ability on chromosome 7q and a secondary locus on chromosome 16p | journal = Hum. Genet. | volume = 112 | issue = 5-6 | pages = 567–72 | year = 2003 | pmid = 12624758 | doi = 10.1007/s00439-003-0911-y | issn = ] which facilitates the tasting of phenylthiocarbamide (PTC)cite journal | author = Prodi DA, Drayna D, Forabosco P, Palmas MA, Maestrale GB, Piras D, Pirastu M, Angius A | title = Bitter taste study in a sardinian genetic isolate supports the association of phenylthiocarbamide sensitivity to the TAS2R38 bitter receptor gene | journal = Chem. Senses | volume = 29 | issue = 8 | pages = 697–702 | year = 2004 | pmid = 15466815 | doi = 10.1093/chemse/bjh074 | issn = ] and propylthiouracil (PROP), cite journal | author = Duffy VB, Davidson AC, Kidd JR, Kidd KK, Speed WC, Pakstis AJ, Reed DR, Snyder DJ, Bartoshuk LM | title = Bitter receptor gene (TAS2R38), 6-n-propylthiouracil (PROP) bitterness and alcohol intake | journal = Alcohol. Clin. Exp. Res. | volume = 28 | issue = 11 | pages = 1629–37 | year = 2004 | pmid = 15547448 | doi = 10.1097/01.ALC.0000145789.55183.D4. | issn = ] , although it does not explain supertasting cite journal | author = Hayes JE, Bartoshuk LM, Kidd JR, Duffy VB | title = Supertasting and PROP Bitterness Depends on More Than the TAS2R38 Gene | journal = Chem Senses | volume = 33 | issue = 3 | pages = 255–65 | year = 2008 | pmid = 18209019 | doi = 10.1093/chemse/bjm084 | issn = ] .

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Margolskee RF |title=Molecular mechanisms of bitter and sweet taste transduction. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 1–4 |year= 2002 |pmid= 11696554 |doi= 10.1074/jbc.R100054200
*cite journal | author=Montmayeur JP, Matsunami H |title=Receptors for bitter and sweet taste. |journal=Curr. Opin. Neurobiol. |volume=12 |issue= 4 |pages= 366–71 |year= 2002 |pmid= 12139982 |doi=
*cite journal | author=Kim UK, Drayna D |title=Genetics of individual differences in bitter taste perception: lessons from the PTC gene. |journal=Clin. Genet. |volume=67 |issue= 4 |pages= 275–80 |year= 2005 |pmid= 15733260 |doi= 10.1111/j.1399-0004.2004.00361.x
*cite journal | author=Anne-Spence M, Falk CT, Neiswanger K, "et al." |title=Estimating the recombination frequency for the PTC-Kell linkage. |journal=Hum. Genet. |volume=67 |issue= 2 |pages= 183–6 |year= 1984 |pmid= 6745938 |doi=
*cite journal | author=Bufe B, Hofmann T, Krautwurst D, "et al." |title=The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides. |journal=Nat. Genet. |volume=32 |issue= 3 |pages= 397–401 |year= 2002 |pmid= 12379855 |doi= 10.1038/ng1014
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zhang Y, Hoon MA, Chandrashekar J, "et al." |title=Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. |journal=Cell |volume=112 |issue= 3 |pages= 293–301 |year= 2003 |pmid= 12581520 |doi=
*cite journal | author=Conte C, Ebeling M, Marcuz A, "et al." |title=Identification and characterization of human taste receptor genes belonging to the TAS2R family. |journal=Cytogenet. Genome Res. |volume=98 |issue= 1 |pages= 45–53 |year= 2003 |pmid= 12584440 |doi= 10.1159/000068546
*cite journal | author=Kim UK, Jorgenson E, Coon H, "et al." |title=Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. |journal=Science |volume=299 |issue= 5610 |pages= 1221–5 |year= 2003 |pmid= 12595690 |doi= 10.1126/science.1080190
*cite journal | author=Drayna D, Coon H, Kim UK, "et al." |title=Genetic analysis of a complex trait in the Utah Genetic Reference Project: a major locus for PTC taste ability on chromosome 7q and a secondary locus on chromosome 16p. |journal=Hum. Genet. |volume=112 |issue= 5-6 |pages= 567–72 |year= 2003 |pmid= 12624758 |doi= 10.1007/s00439-003-0911-y
*cite journal | author=Scherer SW, Cheung J, MacDonald JR, "et al." |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423
*cite journal | author=Wooding S, Kim UK, Bamshad MJ, "et al." |title=Natural selection and molecular evolution in PTC, a bitter-taste receptor gene. |journal=Am. J. Hum. Genet. |volume=74 |issue= 4 |pages= 637–46 |year= 2004 |pmid= 14997422 |doi= 10.1086/383092
*cite journal | author=Pronin AN, Tang H, Connor J, Keung W |title=Identification of ligands for two human bitter T2R receptors. |journal=Chem. Senses |volume=29 |issue= 7 |pages= 583–93 |year= 2005 |pmid= 15337684 |doi= 10.1093/chemse/bjh064
*cite journal | author=Prodi DA, Drayna D, Forabosco P, "et al." |title=Bitter taste study in a sardinian genetic isolate supports the association of phenylthiocarbamide sensitivity to the TAS2R38 bitter receptor gene. |journal=Chem. Senses |volume=29 |issue= 8 |pages= 697–702 |year= 2005 |pmid= 15466815 |doi= 10.1093/chemse/bjh074
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Fischer A, Gilad Y, Man O, Pääbo S |title=Evolution of bitter taste receptors in humans and apes. |journal=Mol. Biol. Evol. |volume=22 |issue= 3 |pages= 432–6 |year= 2005 |pmid= 15496549 |doi= 10.1093/molbev/msi027
*cite journal | author=Go Y, Satta Y, Takenaka O, Takahata N |title=Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates. |journal=Genetics |volume=170 |issue= 1 |pages= 313–26 |year= 2006 |pmid= 15744053 |doi= 10.1534/genetics.104.037523

ee also

* Supertaster

External links

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