Prolactin-releasing peptide receptor

The prolactin-releasing hormone receptor (PRLHR) is a G-protein coupled receptorcite journal | author = Marchese A, Heiber M, Nguyen T, Heng HH, Saldivia VR, Cheng R, Murphy PM, Tsui LC, Shi X, Gregor P | title = Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors | journal = Genomics | volume = 29 | issue = 2 | pages = 335–44 | year = 1995 | pmid = 8666380 | doi = | issn = ] that binds the prolactin releasing hormone.cite journal | author = Hinuma S, Habata Y, Fujii R, Kawamata Y, Hosoya M, Fukusumi S, Kitada C, Masuo Y, Asano T, Matsumoto H, Sekiguchi M, Kurokawa T, Nishimura O, Onda H, Fujino M | title = A prolactin-releasing peptide in the brain | journal = Nature | volume = 393 | issue = 6682 | pages = 272–6 | year = 1998 | pmid = 9607765 | doi = 10.1038/30515 | issn = ]

PBB_Summary
section_title =
summary_text = PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002). [supplied by OMIM] cite web | title = Entrez Gene: PRLHR prolactin releasing hormone receptor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2834| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hinuma S, Onda H, Fujino M |title=The quest for novel bioactive peptides utilizing orphan seven-transmembrane-domain receptors. |journal=J. Mol. Med. |volume=77 |issue= 6 |pages= 495–504 |year= 1999 |pmid= 10475064 |doi=
*cite journal | author=Marchese A, Heiber M, Nguyen T, "et al." |title=Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors. |journal=Genomics |volume=29 |issue= 2 |pages= 335–44 |year= 1996 |pmid= 8666380 |doi=
*cite journal | author=Hinuma S, Habata Y, Fujii R, "et al." |title=A prolactin-releasing peptide in the brain. |journal=Nature |volume=393 |issue= 6682 |pages= 272–6 |year= 1998 |pmid= 9607765 |doi= 10.1038/30515
*cite journal | author=Fujii R, Fukusumi S, Hosoya M, "et al." |title=Tissue distribution of prolactin-releasing peptide (PrRP) and its receptor. |journal=Regul. Pept. |volume=83 |issue= 1 |pages= 1–10 |year= 1999 |pmid= 10498338 |doi=
*cite journal | author=Langmead CJ, Szekeres PG, Chambers JK, "et al." |title=Characterization of the binding of [(125)I] -human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. |journal=Br. J. Pharmacol. |volume=131 |issue= 4 |pages= 683–8 |year= 2000 |pmid= 11030716 |doi= 10.1038/sj.bjp.0703617
*cite journal | author=Lin SH, Arai AC, Wang Z, "et al." |title=The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering. |journal=Mol. Pharmacol. |volume=60 |issue= 5 |pages= 916–23 |year= 2001 |pmid= 11641419 |doi=
*cite journal | author=Ozawa A, Yamada M, Satoh T, "et al." |title=Transcriptional regulation of the human PRL-releasing peptide (PrRP) receptor gene by a dopamine 2 Receptor agonist: cloning and characterization of the human PrRP receptor gene and its promoter region. |journal=Mol. Endocrinol. |volume=16 |issue= 4 |pages= 785–98 |year= 2002 |pmid= 11923475 |doi=
*cite journal | author=Takahashi K, Totsune K, Murakami O, "et al." |title=Expression of prolactin-releasing peptide and its receptor in the human adrenal glands and tumor tissues of adrenocortical tumors, pheochromocytomas and neuroblastomas. |journal=Peptides |volume=23 |issue= 6 |pages= 1135–40 |year= 2003 |pmid= 12126742 |doi=
*cite journal | author=Kemp DM, Lin JC, Ubeda M, Habener JF |title=NRSF/REST confers transcriptional repression of the GPR10 gene via a putative NRSE/RE-1 located in the 5' promoter region. |journal=FEBS Lett. |volume=531 |issue= 2 |pages= 193–8 |year= 2002 |pmid= 12417311 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Bhattacharyya S, Luan J, Challis B, "et al." |title=Association of polymorphisms in GPR10, the gene encoding the prolactin-releasing peptide receptor with blood pressure, but not obesity, in a U.K. Caucasian population. |journal=Diabetes |volume=52 |issue= 5 |pages= 1296–9 |year= 2003 |pmid= 12716769 |doi=
*cite journal | author=Deloukas P, Earthrowl ME, Grafham DV, "et al." |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ellacott KL, Donald EL, Clarkson P, "et al." |title=Characterization of a naturally-occurring polymorphism in the UHR-1 gene encoding the putative rat prolactin-releasing peptide receptor. |journal=Peptides |volume=26 |issue= 4 |pages= 675–81 |year= 2005 |pmid= 15752583 |doi= 10.1016/j.peptides.2004.11.020
*cite journal | author=Lagerström MC, Fredriksson R, Bjarnadóttir TK, "et al." |title=Origin of the prolactin-releasing hormone (PRLH) receptors: evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution. |journal=Genomics |volume=85 |issue= 6 |pages= 688–703 |year= 2005 |pmid= 15885496 |doi= 10.1016/j.ygeno.2005.02.007
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406

External links

* [http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1350 IUPHAR GPCR Database - Prolactin-releasing peptide receptor]
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