TAS2R4

Taste receptor, type 2, member 4, also known as TAS2R4, is a human gene.cite web | title = Entrez Gene: TAS2R4 taste receptor, type 2, member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50832| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception.cite web | title = Entrez Gene: TAS2R4 taste receptor, type 2, member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50832| accessdate = ]

ee also

* Taste receptor

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kinnamon SC |title=A plethora of taste receptors. |journal=Neuron |volume=25 |issue= 3 |pages= 507–10 |year= 2000 |pmid= 10774719 |doi=
*cite journal | author=Margolskee RF |title=Molecular mechanisms of bitter and sweet taste transduction. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 1–4 |year= 2002 |pmid= 11696554 |doi= 10.1074/jbc.R100054200
*cite journal | author=Montmayeur JP, Matsunami H |title=Receptors for bitter and sweet taste. |journal=Curr. Opin. Neurobiol. |volume=12 |issue= 4 |pages= 366–71 |year= 2002 |pmid= 12139982 |doi=
*cite journal | author=Adler E, Hoon MA, Mueller KL, "et al." |title=A novel family of mammalian taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 693–702 |year= 2000 |pmid= 10761934 |doi=
*cite journal | author=Chandrashekar J, Mueller KL, Hoon MA, "et al." |title=T2Rs function as bitter taste receptors. |journal=Cell |volume=100 |issue= 6 |pages= 703–11 |year= 2000 |pmid= 10761935 |doi=
*cite journal | author=Firestein S |title=The good taste of genomics. |journal=Nature |volume=404 |issue= 6778 |pages= 552–3 |year= 2000 |pmid= 10766221 |doi= 10.1038/35007167
*cite journal | author=Matsunami H, Montmayeur JP, Buck LB |title=A family of candidate taste receptors in human and mouse. |journal=Nature |volume=404 |issue= 6778 |pages= 601–4 |year= 2000 |pmid= 10766242 |doi= 10.1038/35007072
*cite journal | author=Ueda T, Ugawa S, Ishida Y, "et al." |title=Identification of coding single-nucleotide polymorphisms in human taste receptor genes involving bitter tasting. |journal=Biochem. Biophys. Res. Commun. |volume=285 |issue= 1 |pages= 147–51 |year= 2001 |pmid= 11437385 |doi= 10.1006/bbrc.2001.5136
*cite journal | author=Zhang Y, Hoon MA, Chandrashekar J, "et al." |title=Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. |journal=Cell |volume=112 |issue= 3 |pages= 293–301 |year= 2003 |pmid= 12581520 |doi=
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Fischer A, Gilad Y, Man O, Pääbo S |title=Evolution of bitter taste receptors in humans and apes. |journal=Mol. Biol. Evol. |volume=22 |issue= 3 |pages= 432–6 |year= 2005 |pmid= 15496549 |doi= 10.1093/molbev/msi027
*cite journal | author=Go Y, Satta Y, Takenaka O, Takahata N |title=Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates. |journal=Genetics |volume=170 |issue= 1 |pages= 313–26 |year= 2006 |pmid= 15744053 |doi= 10.1534/genetics.104.037523

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