FZD1

Frizzled homolog 1 (Drosophila), also known as FZD1, is a human gene.cite web | title = Entrez Gene: FZD1 frizzled homolog 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8321| accessdate = ]

PBB_Summary
section_title =
summary_text = Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.cite web | title = Entrez Gene: FZD1 frizzled homolog 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8321| accessdate = ]

ee also

* Frizzled

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Tanaka S, Akiyoshi T, Mori M, "et al." |title=A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 17 |pages= 10164–9 |year= 1998 |pmid= 9707618 |doi=
*cite journal | author=Sagara N, Toda G, Hirai M, "et al." |title=Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7. |journal=Biochem. Biophys. Res. Commun. |volume=252 |issue= 1 |pages= 117–22 |year= 1998 |pmid= 9813155 |doi= 10.1006/bbrc.1998.9607
*cite journal | author=Gazit A, Yaniv A, Bafico A, "et al." |title=Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response. |journal=Oncogene |volume=18 |issue= 44 |pages= 5959–66 |year= 1999 |pmid= 10557084 |doi= 10.1038/sj.onc.1202985
*cite journal | author=DeCostanzo AJ, Huang XP, Wang HY, Malbon CC |title=The Frizzled-1/(beta(2))-adrenergic receptor chimera: pharmacological properties of a unique G protein-linked receptor. |journal=Naunyn Schmiedebergs Arch. Pharmacol. |volume=365 |issue= 5 |pages= 341–8 |year= 2002 |pmid= 12012019 |doi= 10.1007/s00210-002-0540-3
*cite journal | author=Hering H, Sheng M |title=Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95. |journal=FEBS Lett. |volume=521 |issue= 1-3 |pages= 185–9 |year= 2002 |pmid= 12067714 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Scherer SW, Cheung J, MacDonald JR, "et al." |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Zilberberg A, Yaniv A, Gazit A |title=The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway. |journal=J. Biol. Chem. |volume=279 |issue= 17 |pages= 17535–42 |year= 2004 |pmid= 14739301 |doi= 10.1074/jbc.M311292200
*cite journal | author=Wu J, Klein TJ, Mlodzik M |title=Subcellular localization of frizzled receptors, mediated by their cytoplasmic tails, regulates signaling pathway specificity. |journal=PLoS Biol. |volume=2 |issue= 7 |pages= E158 |year= 2006 |pmid= 15252441 |doi= 10.1371/journal.pbio.0020158
*cite journal | author=Omoto S, Hayashi T, Kitahara K, "et al." |title=Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R). |journal=Ophthalmic Genet. |volume=25 |issue= 2 |pages= 81–90 |year= 2004 |pmid= 15370539 |doi= 10.1080/13816810490514270
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Yang L, Yamasaki K, Shirakata Y, "et al." |title=Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes. |journal=J. Dermatol. Sci. |volume=42 |issue= 2 |pages= 111–9 |year= 2006 |pmid= 16442268 |doi= 10.1016/j.jdermsci.2005.12.011

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes