FZD5

Frizzled homolog 5 (Drosophila), also known as FZD5, is a human gene.cite web | title = Entrez Gene: FZD5 frizzled homolog 5 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7855| accessdate = ]

PBB_Summary
section_title =
summary_text = Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.cite web | title = Entrez Gene: FZD5 frizzled homolog 5 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7855| accessdate = ]

ee also

* Frizzled

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wang Y, Macke JP, Abella BS, "et al." |title=A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. |journal=J. Biol. Chem. |volume=271 |issue= 8 |pages= 4468–76 |year= 1996 |pmid= 8626800 |doi=
*cite journal | author=He X, Saint-Jeannet JP, Wang Y, "et al." |title=A member of the Frizzled protein family mediating axis induction by Wnt-5A. |journal=Science |volume=275 |issue= 5306 |pages= 1652–4 |year= 1997 |pmid= 9054360 |doi=
*cite journal | author=Finch PW, He X, Kelley MJ, "et al." |title=Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 13 |pages= 6770–5 |year= 1997 |pmid= 9192640 |doi=
*cite journal | author=Tanaka S, Akiyoshi T, Mori M, "et al." |title=A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 17 |pages= 10164–9 |year= 1998 |pmid= 9707618 |doi=
*cite journal | author=Tamai K, Semenov M, Kato Y, "et al." |title=LDL-receptor-related proteins in Wnt signal transduction. |journal=Nature |volume=407 |issue= 6803 |pages= 530–5 |year= 2000 |pmid= 11029007 |doi= 10.1038/35035117
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Saitoh T, Hirai M, Katoh M |title=Molecular cloning and characterization of human Frizzled-5 gene on chromosome 2q33.3-q34 region. |journal=Int. J. Oncol. |volume=19 |issue= 1 |pages= 105–10 |year= 2001 |pmid= 11408929 |doi=
*cite journal | author=Yao R, Maeda T, Takada S, Noda T |title=Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled. |journal=Biochem. Biophys. Res. Commun. |volume=286 |issue= 4 |pages= 771–8 |year= 2001 |pmid= 11520064 |doi= 10.1006/bbrc.2001.5430
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Weidler C, Schaumburger J, Miller LE, "et al." |title=Synovial density of frizzled 5-positive cells does not differ between patients with RA and OA and is independent of inflammation. |journal=J. Rheumatol. |volume=31 |issue= 9 |pages= 1874–5 |year= 2004 |pmid= 15338479 |doi=
*cite journal | author=Omoto S, Hayashi T, Kitahara K, "et al." |title=Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R). |journal=Ophthalmic Genet. |volume=25 |issue= 2 |pages= 81–90 |year= 2004 |pmid= 15370539 |doi= 10.1080/13816810490514270
*cite journal | author=Holmen SL, Robertson SA, Zylstra CR, Williams BO |title=Wnt-independent activation of beta-catenin mediated by a Dkk1-Fz5 fusion protein. |journal=Biochem. Biophys. Res. Commun. |volume=328 |issue= 2 |pages= 533–9 |year= 2005 |pmid= 15694380 |doi= 10.1016/j.bbrc.2005.01.009
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466
*cite journal | author=Blumenthal A, Ehlers S, Lauber J, "et al." |title=The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. |journal=Blood |volume=108 |issue= 3 |pages= 965–73 |year= 2006 |pmid= 16601243 |doi= 10.1182/blood-2005-12-5046
*cite journal | author=Yamamoto H, Komekado H, Kikuchi A |title=Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin. |journal=Dev. Cell |volume=11 |issue= 2 |pages= 213–23 |year= 2006 |pmid= 16890161 |doi= 10.1016/j.devcel.2006.07.003
*cite journal | author=Katoh Y, Katoh M |title=Conserved POU-binding site linked to SP1-binding site within FZD5 promoter: Transcriptional mechanisms of FZD5 in undifferentiated human ES cells, fetal liver/spleen, adult colon, pancreatic islet, and diffuse-type gastric cancer. |journal=Int. J. Oncol. |volume=30 |issue= 3 |pages= 751–5 |year= 2007 |pmid= 17273778 |doi=

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