LRP6

LRP6

Low density lipoprotein receptor-related protein 6, also known as LRP6, is a human gene.cite web | title = Entrez Gene: LRP6 low density lipoprotein receptor-related protein 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4040| accessdate = ]

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References

Further reading

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*cite journal | author=He X, Semenov M, Tamai K, Zeng X |title=LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. |journal=Development |volume=131 |issue= 8 |pages= 1663–77 |year= 2004 |pmid= 15084453 |doi= 10.1242/dev.01117
*cite journal | author=Hillier LD, Lennon G, Becker M, "et al." |title=Generation and analysis of 280,000 human expressed sequence tags. |journal=Genome Res. |volume=6 |issue= 9 |pages= 807–28 |year= 1997 |pmid= 8889549 |doi=
*cite journal | author=Brown SD, Twells RC, Hey PJ, "et al." |title=Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family. |journal=Biochem. Biophys. Res. Commun. |volume=248 |issue= 3 |pages= 879–88 |year= 1998 |pmid= 9704021 |doi= 10.1006/bbrc.1998.9061
*cite journal | author=Baens M, Wlodarska I, Corveleyn A, "et al." |title=A physical, transcript, and deletion map of chromosome region 12p12.3 flanked by ETV6 and CDKN1B: hypermethylation of the LRP6 CpG island in two leukemia patients with hemizygous del(12p). |journal=Genomics |volume=56 |issue= 1 |pages= 40–50 |year= 1999 |pmid= 10036184 |doi= 10.1006/geno.1998.5685
*cite journal | author=Tamai K, Semenov M, Kato Y, "et al." |title=LDL-receptor-related proteins in Wnt signal transduction. |journal=Nature |volume=407 |issue= 6803 |pages= 530–5 |year= 2000 |pmid= 11029007 |doi= 10.1038/35035117
*cite journal | author=Mao B, Wu W, Li Y, "et al." |title=LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. |journal=Nature |volume=411 |issue= 6835 |pages= 321–5 |year= 2001 |pmid= 11357136 |doi= 10.1038/35077108
*cite journal | author=Semënov MV, Tamai K, Brott BK, "et al." |title=Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. |journal=Curr. Biol. |volume=11 |issue= 12 |pages= 951–61 |year= 2001 |pmid= 11448771 |doi=
*cite journal | author=Li L, Mao J, Sun L, "et al." |title=Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled. |journal=J. Biol. Chem. |volume=277 |issue= 8 |pages= 5977–81 |year= 2002 |pmid= 11742004 |doi= 10.1074/jbc.M111131200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Caricasole A, Ferraro T, Iacovelli L, "et al." |title=Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins. |journal=J. Biol. Chem. |volume=278 |issue= 39 |pages= 37024–31 |year= 2003 |pmid= 12857724 |doi= 10.1074/jbc.M300191200
*cite journal | author=Liu G, Bafico A, Harris VK, Aaronson SA |title=A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor. |journal=Mol. Cell. Biol. |volume=23 |issue= 16 |pages= 5825–35 |year= 2003 |pmid= 12897152 |doi=
*cite journal | author=Zilberberg A, Yaniv A, Gazit A |title=The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway. |journal=J. Biol. Chem. |volume=279 |issue= 17 |pages= 17535–42 |year= 2004 |pmid= 14739301 |doi= 10.1074/jbc.M311292200
*cite journal | author=Wang X, Adhikari N, Li Q, Hall JL |title=LDL receptor-related protein LRP6 regulates proliferation and survival through the Wnt cascade in vascular smooth muscle cells. |journal=Am. J. Physiol. Heart Circ. Physiol. |volume=287 |issue= 6 |pages= H2376–83 |year= 2005 |pmid= 15271658 |doi= 10.1152/ajpheart.01173.2003
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Li Y, Lu W, He X, "et al." |title=LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distribution. |journal=Oncogene |volume=23 |issue= 56 |pages= 9129–35 |year= 2005 |pmid= 15516984 |doi= 10.1038/sj.onc.1208123
*cite journal | author=Semënov M, Tamai K, He X |title=SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor. |journal=J. Biol. Chem. |volume=280 |issue= 29 |pages= 26770–5 |year= 2005 |pmid= 15908424 |doi= 10.1074/jbc.M504308200
*cite journal | author=Li Y, Chen J, Lu W, "et al." |title=Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding. |journal=J. Cell. Sci. |volume=118 |issue= Pt 22 |pages= 5305–14 |year= 2006 |pmid= 16263759 |doi= 10.1242/jcs.02651
*cite journal | author=Mi K, Dolan PJ, Johnson GV |title=The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activity. |journal=J. Biol. Chem. |volume=281 |issue= 8 |pages= 4787–94 |year= 2006 |pmid= 16365045 |doi= 10.1074/jbc.M508657200

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