- Deliriant
-
The deliriants (or anticholinergics) are a special class of acetylcholine-inhibitor hallucinogen. The term was introduced by David F. Duncan and Robert S. Gold to distinguish these drugs from psychedelics, such as LSD, due to their primary effect being one of inducing a medical state of frank delirium.[1]
Effects
The delirium produced is characterized by stupor, utter confusion, confabulation, and regression to "phantom" behaviors such as disrobing and plucking. Other commonly reported behaviors include holding full and lifelike conversations with imagined people, finishing a complex, multi-stage action (such as getting dressed) and then suddenly discovering you had not even begun yet, and being unable to recognize one's own reflection in a mirror.
The effects have been likened to sleepwalking, a fugue state or a psychotic episode (particularly in that the subject has minimal control over their actions and little to no recall of the experience). This is a notable departure from typical hallucinogens.
Members
Included in this group are such Solanaceae plants as deadly nightshade, nutmeg, "floripondio" or feingold angel's trumpet/tears, mandrake, henbane, scopolia and datura (containing tropane alkaloids sometimes referred to as the Belladonna alkaloids), as well as a number of pharmaceutical drugs such as the antihistamine diphenhydramine (Benadryl) and the antiemetics dimenhydrinate (Dramamine or Gravol) and scopolamine. The chemical warfare agent BZ (3-quinuclidinyl benzilate) is a highly potent anticholinergic military incapacitating agent.
Recreational use
Despite the fully legal status of several common deliriant plants, deliriants are largely unpopular as recreational drugs due to the severe and unpleasant nature of the hallucinations produced.
User reports of recreational deliriant usage on the Erowid website generally indicate a firm unwillingness to repeat the experience. In addition to their potentially dangerous mental effects (accidents during deliriant experiences are common [2]) many tropane alkaloids (such as scopolamine and atropine, the primary alkaloids in Datura stramonium) are highly poisonous and can cause death due to tachycardia-induced heart failure and hyperthermia even in small doses. Other physical effects include intense and painful drying of the eyes and mucous membranes, as well as a pronounced dilation of the pupils which can last for several days resulting in sensitivity to light, blurry vision and inability to read.
Mythology
Deliriants are commonly featured in European mythology, including the plants mandrake, deadly nightshade, and various datura species.
Classes of Deliriants
Anticholinergics
- Tropanes
- Disubstituted glycolic acid esters
Antihistamines
See also
References
- ^ Duncan, D. F., and Gold, R. S. (1982). Drugs and the Whole Person. New York: John Wiley & Sons
- ^ "Datura Items". http://www.lycaeum.org/mv/mu/datura.html. Retrieved 2011-01-04.
Recreational drug use Major recreational drugs Amphetamine · Arecoline (Areca) · Betel · Caffeine (Coffee · Tea) · Cathinone (Khat) · Cocaine (Coca) · Ephedrine (Ephedra) · Mephedrone · Methamphetamine · Methylphenidate · Nicotine (Tobacco) · Theobromine (Cocoa)EntactogensHallucinogensBufotenin ( Psychoactive toads · Vilca · Yopo) · DMT (Ayahuasca) · LSA · LSD-25 · Mescaline (Peruvian Torch · Peyote · San Pedro) · Psilocybin / Psilocin (Psilocybin mushrooms)DXM · Inhalants (Nitrous oxide · alkyl nitrites – poppers, such as amyl nitrite) · Ketamine · Methoxetamine · Muscimol (Amanita muscaria) · PCP · Salvinorin A (Salvia divinorum)DeliriantsAtropine and Scopolamine (Datura · Deadly Nightshade · Henbane · Mandrake) · Dimenhydrinate · DiphenhydramineCannabinoidsDrug subculture 420 · Cannabis cultivation · Cannabis smoking · Legal history of cannabis in the United States · Legality of cannabis · Marijuana Policy Project · Medical cannabis · NORML · Religious and spiritual use of cannabis · Stoner filmOtherProblems with drug use Abuse · Dependence (Prevention · Opioid replacement therapy · Rehabilitation · Responsible use) · Drug-related crime · Fetal alcohol spectrum disorder · Illegal drug trade · Long-term effects of cannabis · Neurotoxicity · OverdoseLegality of drug use InternationalState levelDrug policy
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5-HT2AR agonists- Lysergamides: AL-LAD
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Dissociatives
NMDAR antagonists- Arylcyclohexylamines: 3-MeO-PCP
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Deliriants
mAChR antagonists- 3-Quinuclidinyl benzilate
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- CAR-226,086
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- Tolterodine
- Trihexyphenidyl
- Tripelennamine
- Triprolidine
- WIN-2299
Miscellaneous - Apomorphine
- Bromocriptine
- Cabergoline
- Lisuride
- Memantine
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- Pramipexole
- Ropinirole
- Rotigotine
- Butane
- Chloroform
- Diethyl Ether (Ether)
- Enflurane
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κOR agonists- 2-EMSB
- 2-MMSB
- Alazocine
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- Noscapine (Narcotine)
OthersCategories:- Deliriants
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