JWH-030

Drugbox
IUPAC_name = naphthalen-1-yl-(1-pentylpyrrol-3-yl)methanone

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PubChem= 9971539
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C=20 | H=21 | N=1 | O=1
molecular_weight = 291.386 g/mol
smiles = CCCCCn3cc(cc3)C(=O)c1cccc2ccccc12
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JWH-030 is a drug which is a cannabinoid receptor agonist. [Lainton JAH, Huffman JW, Martin BR,Compton DR. "Tetrahedron Letters". 1995; 36:1401.] It has analgesic effects and is used in scientific research. [Pertwee RG, Griffin, G, Lainton JAH, Huffman JW. "European Journal of Pharmacology". 1995; 284:241.] It is a partial agonist at CB₁ receptors, with a Ki of 87nM, making it around half the potency of THC. [Griffin G, Atkinson PJ, Showalter VM, Martin BR, Abood ME. Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3- [35S] thio)-triphosphate binding assay in rat cerebellar membranes. "Journal of Pharmacology and Experimental Therapeutics". 1998 May;285(2):553-60. PMID 9580597]

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