NEFA (drug)

NEFA (drug)
NEFA (drug)
Systematic (IUPAC) name
(4aR,9aS)-N-Ethyl-4,4a,9,9a-tetrahydro-1H-fluoren-4a-amine
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
ATC code  ?
Chemical data
Formula C15H19N 
Mol. mass 213.3181 g/mol
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NEFA is a moderate affinity NMDA antagonist (IC50 = 0.51 μM). It is a structural analog of phencyclidine.[1]

References

  1. ^ Dilmore JG, Johnson JW (1998). "Open channel block and alteration of N-methyl-D-aspartic acid receptor gating by an analog of phencyclidine". Biophysical Journal 75 (4): 1801–16. doi:10.1016/S0006-3495(98)77622-2. PMC 1299852. PMID 9746522. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1299852. 


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