Pheniramine

drugbox
IUPAC_name = "N","N"-dimethyl-3-phenyl-3-pyridin-2-yl-propan-1-amine

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CAS_number = 86-21-5
ATC_prefix = R06
ATC_suffix = AB05
PubChem = 4761
DrugBank =
C=16|H=20|N=2
molecular_weight = 240.343 g/mol
bioavailability =
protein_bound =
metabolism = Hepatic hydroxylation, demethylation and glucuronidation
elimination_half-life =
excretion = Renal
pregnancy_AU =
pregnancy_US =
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routes_of_administration = Oral

Pheniramine maleate is an antihistamine used to treat allergic conditions such as hay fever or urticaria. It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine. Derivatives of pheniramine are chlorphenamine and brompheniramine.

Pheniramine is generally sold in combination with other medications, rather than as a stand-alone drug, although some formulations are available containing pheniramine by itself. It is sold under the brand name Avil by the pharmaceutical company Aventis.

See also