Alpha-Ethyltryptamine

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IUPAC_name = 1-(1"H"-indol-3-yl)butan-2-amine

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width = 140
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CAS_number = 2235-90-7
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PubChem = 8367
C=12 | H=16 | N=2
molecular_weight = 188.27 g/mol
smiles = CCC(N)Cc1c [nH] c2ccccc12
melting_point = 222
melting_high = 223
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legal_US = Schedule I
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alpha-Ethyltryptamine (Etryptamine, α-ethyltryptamine, α-ET, or AET), is a psychoactive drug belonging to the tryptamine family. It was explored as an anti-depressant by Upjohn Chemical Company under the name Monase, but was withdrawn from commercial use after a year due to the unacceptable occurrence of agranulocytosis. It was moved into US Schedule I list of illegal substances in 1993. It is structurally related to α-methyltryptamine but its pharmacological effects are very different. α-ET is not a hallucinogenic drug, its effects resemble more that of the empathogen-entactogens like MDMA (Ecstasy). Alexander Shulgin, in TiHKAL, mentions that this compound has been used to alleviate unpleasant symptoms of opiate withdrawal.

Dosage

75-150 mg is commonly consumed orally for entactogenic effects. α-ET has a stereocenter and "S"-(+)-α-ET is the more active stereoisomer.

See also

* TiHKAL
* Indoles

External links

* [http://www.erowid.org/library/books_online/tihkal/tihkal11.shtml TiHKAL entry]
* [http://www.erowid.org/chemicals/aet/aet.shtml α-ET vault on Erowid]