JWH-073

Drugbox
IUPAC_name = naphthalen-1-yl-(1-butylindol-3-yl)methanone

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PubChem = 10471670
DrugBank =
C=23|H=21|N=1|O=1
molecular_weight = 327.42 g/mol
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legal_status = Legal
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JWH-073 is an analgesic drug from the aminoalkylindole family, which acts as a cannabinoid agonist at both the CB₁ and CB₂ receptors. It is somewhat selective for the CB₁ subtype, with affinity at this subtype approximately 5x the affinity at CB₂.cite journal |author=Aung MM, Griffin G, Huffman JW, "et al" |title=Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding |journal=Drug Alcohol Depend |volume=60 |issue=2 |pages=133–40 |year=2000 |month=August |pmid=10940540 |doi=10.1016/S0376-8716(99)00152-0 |url=http://linkinghub.elsevier.com/retrieve/pii/S0376871699001520] The abbreviation JWH stands for John W. Huffman, one of the inventors of the compound.

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