Nalorphine

Nalorphine

Systematic (IUPAC) name
(5α,6α)-17-allyl- 7,8-didehydro- 4,5-epoxymorphinan- 3,6-diol
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	62-67-9 Y
ATC code	V03AB02
PubChem	CID 5284595
IUPHAR ligand	1629
ChemSpider	4447643 Y
UNII	U59WB2WRY2 N
ChEMBL	CHEMBL415284 N
Synonyms	(−)−(5R,6S)-9α-allyl- 4,5-epoxymorphin- 7-en- 3,6-diol
Chemical data
Formula	C19H21NO3
Mol. mass	311.375 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C19H21NO3/c1-2-8-20-9-7-19-12-4-6-15(22)18(19)23-17-14(21)5-3-11(16(17)19)10-13(12)20/h2-6,12-13,15,18,21-22H,1,7-10H2/t12-,13+,15-,18-,19-/m0/s1 Y Key:UIQMVEYFGZJHCZ-SSTWWWIQSA-N Y
N(what is this?)  (verify)

Nalorphine (INN, also known as N-allyl-normorphine) trade names Lethidrone and Nalline. Nalorphine acts at two opioid receptors, at the mu receptor it has antagonistic effects and at the kappa receptors it exerts agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.^[1]

References

1. ^ "Medicine: Drug Detector", Time, Dec. 24, 1956

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.v · Categories: Opioid antagonists Morphinans Phenols Alcohols Alkenes Kappa agonists Semisynthetic opioids Nervous system drug stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат Maharani Laxmi Bai Medical College Minamiaiki Dam Look at other dictionaries: nalorphine — ● nalorphine nom féminin Substance morphinique semi synthétique caractérisée par son antagonisme spécifique vis à vis de la morphine et de ses dérivés …   Encyclopédie Universelle nalorphine — ☆ nalorphine [nal ôr′fēn΄ ] n. [< N al(lylnorm)orphine] a white, crystalline derivative of morphine, C19H21NO3, used, usually in the form of its hydrochloride, to counteract the effects of narcotic overdoses and to aid in diagnosing narcotic… …   English World dictionary nalorphine — noun Etymology: N allyl + morphine Date: circa 1953 a white crystalline compound C19H21NO3 that is derived from morphine and is used in the form of its hydrochloride as a respiratory stimulant to counteract poisoning by morphine and similar… …   New Collegiate Dictionary nalorphine — /nal euhr feen , nal awr feen/, n. Pharm. a white, crystalline, water soluble powder, C19H21NO3, used to nullify respiratory depression due to narcotics and for the diagnosis of addiction to narcotics. [1950 55; N al(lyln)or(mor)phine; see ALLYL …   Universalium nalorphine — noun A drug used to reverse opioid overdose …   Wiktionary nalorphine — An early antagonist of most of the depressant and stimulatory effects of morphine and related narcotic analgesics; precipitates severe withdrawal symptoms in morphine addicts, is used in the diagnosis of suspected morphine addiction, and… …   Medical dictionary nalorphine — n. derivative of morphine used to treat effects of drug overdose and detect a drug addiction (Pharmacology) …   English contemporary dictionary nalorphine — nal·or·phine …   English syllables nalorphine — nal•or•phine [[t]ˈnæl ərˌfin, nælˈɔr fin[/t]] n. a narcotic antagonist, C19H21NO3, chemically related to morphine, used to counteract overdose and to diagnose addiction • Etymology: 1950–55; N al(lyln) or(mor) phine …   From formal English to slang nalorphine — noun a narcotic antagonist (trade name Nalline) that counteracts the effects of narcotics (especially the effects of poisoning by morphine) • Syn: ↑Nalline • Hypernyms: ↑narcotic antagonist …   Useful english dictionary 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”