- Trimethoxyamphetamine
TMAs, also known as trimethoxyamphetamines, are a family of
isomer icpsychedelic hallucinogenic drugs. There exist six different TMAs that differ only in the position of the threemethoxy groups: TMA, TMA-2, TMA-3, TMA-4, TMA-5, and TMA-6. The TMAs are analogs of thephenethylamine cactus alkaloid mescaline . The TMAs aresubstituted amphetamine s, however, their action does not resemble that of the unsubstituted compound "amphetamine", which is astimulant and not a psychedelic. It is reported that some TMA's elicit a range of emotions ranging from sadness to empathy and euphoria. Several TMAs were first synthesized by the chemistAlexander Shulgin . Synthesis data as well ashuman activity data has been published in the book "PiHKAL (Phenethylamines i Have Known And Loved)".The most important TMA compound from a pharmacological standpoint is TMA-2, as this isomer has been much more widely used as a recreational drug and sold on the black market and as a "
research chemical "; TMA (sometimes referred to as "mescalamphetamine") and TMA-6 have also been used in this way to a lesser extent. These three isomers are significantly more active as hallucinogenic drugs, and have consequently been placed onto the illegal drug schedules in some countries such as theNetherlands andJapan . The other three isomers TMA-3, TMA-4 and TMA-5 are not known to have been used as recreational drugs to any great extent, and remain obscure scientific curiosities.TMAs
See also
*
Psychedelic
*Hallucinogenic drug
*Phenethylamine s
*Amphetamine s
*Recreational drug use External links
* PiHKAL entries:
** [http://www.erowid.org/library/books_online/pihkal/pihkal157.shtml TMA]
** [http://www.erowid.org/library/books_online/pihkal/pihkal158.shtml TMA-2]
** [http://www.erowid.org/library/books_online/pihkal/pihkal159.shtml TMA-3]
** [http://www.erowid.org/library/books_online/pihkal/pihkal160.shtml TMA-4]
** [http://www.erowid.org/library/books_online/pihkal/pihkal161.shtml TMA-5]
** [http://www.erowid.org/library/books_online/pihkal/pihkal162.shtml TMA-6]
* [http://www.erowid.org/chemicals/tma2/tma2.shtml Erowid TMA vault]
* [http://www.emcdda.europa.eu/index.cfm?fuseaction=public.Content&nNodeID=431 EMCDDA Report on the risk assessment of TMA-2 in the framework of the joint action on new synthetic drugs]
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