Renin — Protbox Name=Renin Photo=Renin.png Caption=Molecular structure of renin HGNCid = 9958 Symbol = REN AltSymbols = Names=Angiotensinogenase Chromosome = 1 Arm = q Band = 32 LocusSupplementaryData = Gene= Gene type= Protein length=406 Molecular… … Wikipedia
Discovery and development of renin inhibitors — Renin inhibitors are antihypertensive drugs that inhibit the first and rate limiting step of the renin angiotensin aldosterone system (RAAS). Since the 1970s scientists have been trying to develop potent inhibitors with acceptable oral… … Wikipedia
Renin-angiotensin system — The renin angiotensin system (RAS) or the renin angiotensin aldosterone system (RAAS) is a hormone system that regulates blood pressure and water (fluid) balance. When blood pressure is low, the kidneys secrete renin. Renin stimulates the… … Wikipedia
ACE inhibitor — ACE inhibitors, or inhibitors of Angiotensin Converting Enzyme, are a group of pharmaceuticals that are used primarily in treatment of hypertension and congestive heart failure, in some cases as the drugs of first choice.Clinical useIndications… … Wikipedia
Nucleic acid inhibitor — Image illustrates DNA, RNA, and protein synthesis. The first two are nucleic acids. A Nucleic acid inhibitor is a type of antibacterial that acts by inhibiting the production of nucleic acids. There are two major classes: DNA inhibitors and RNA… … Wikipedia
Plasminogen activator inhibitor-1 — Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 PAI 1 in complex with the SMB domain of Vitronectin PDB 1OC0 … Wikipedia
Protease-Inhibitor — Protease Inhibitoren (PI) sind Moleküle, die Peptidasen (alter Name: Proteasen) hemmen und damit den Abbau von Proteinen verhindern können. Oft handelt es sich dabei selbst um Proteine. Auch eine Gruppe von Arzneistoffen, die zur Behandlung von… … Deutsch Wikipedia
Monoamine oxidase inhibitor — MAOI redirects here. For the Easter Island statues, see Moai. Monoamine oxidase Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs prescribed for the treatment of depression. They are particularly effective in treating… … Wikipedia
Phosphodiesterase inhibitor — A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), therefore preventing the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and… … Wikipedia
Dihydrofolate reductase inhibitor — A dihydrofolate reductase inhibitor is a molecule that inhibits the function of dihydrofolate reductase, and is a type of antifolate. Since folate is needed by rapidly dividing cells to make thymine, this effect may be used to therapeutic… … Wikipedia
